Endocytosis (clathrin)

Question 1

After binding, __________ begins to attach to adaptin

Answer 1

Clathrin

Question 2

When clathrin binds to Adaptin, it forms a ___________

Answer 2

Clathrin basket

Question 3

__________ coils around the membrane.

Answer 3

Dynamin

Question 4

What does dynamin use to tighten around the membrane?

Answer 4

GTP

Question 5

What happens when dynamin brings the membrane completely together?

Answer 5

It causes the vesicles to pop off

Question 6

Clathrin basket breaks apart using _______ and _______

Answer 6

Auxilin and HSP 70

Question 7

Auxilin and HSP 70 use _____ to bind to clathrin.

Answer 7

ATP

Question 8

When the vesicle fuses with the early endosome, what happens?

Answer 8

It drops of the receptor and ligand

Question 9

After fusing with the early endosome, _____ gets pumped into the early endosome.

Answer 9

Protons

Question 10

At what pH does the receptor and ligand separate?

Answer 10

At pH 4 or 5

Question 11

Where does the vesicle of empty receptors go?

Answer 11

To the plasma membrane

Question 12

Where do the vesicle with ligands go?

Answer 12

To the late endosome

Question 13

How does the ligand travel to the late endosome?

Answer 13

Through molecular motors

Question 14

Which molecular motor walls from the positive end to the negative end?

Answer 14

Dynein

Question 15

Which molecular motors walk on microtubules?

Answer 15

Dynein and kinesin

Question 16

What shape is clathrin?

Answer 16

It’s a three legged molecule; triskellion

Question 17

What does the lysosome dump into the late endosome?

Answer 17

Enzymes

Question 18

When the enzymes are dumped into the late endosome, what happens?

Answer 18

The ligand gets broken down into cholesterol

Question 19

Microtubules extend from the inner part of the cell which is ___ to the outer part of the cell which is ____

Answer 19

Negative; positive

Question 20

In step 1 of the clathrin mediated endocytosis __________ binds to a receptor.

Answer 20

Adaptin