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Biology 411 > Cell Junctions > Flashcards

Cell Junctions Flashcards

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1
Q

Define: cadherins

A

Calcium dependent adhesion

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2
Q

What are the 4 different kinds of cell junction proteins?

A
  1. Cadherins
  2. Integrins
  3. Ig-superfamily
  4. Selections
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3
Q

Are all the links between cells permanent?

A

No

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4
Q

Which are the 4 cell-to-cell junction types?

A
  1. Tight junction
  2. Belt desmosome
  3. Spot desmosome
  4. Gap junction
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5
Q

Which desmosome is connects the cell to the ECM?

A

Hemidesmosome

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6
Q

What is the main goal of a desmosome?

A

To give a cell strength

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7
Q

The three types of desmosomes are:

A

Spot, belt and hemi

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8
Q

What are the proteins of a spot desmosome?

A

Cadherins: desmoglein and desmocolin
Plakin proteins: plakoglobin and desmoplakin
Tonifilaments: keratin

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9
Q

What do the keratin filaments of the spot desmosome do?

A

Connect spot desmosome to spot desmosome

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10
Q

What is the cell junction?

A

An intercellular bridge with integral proteins that often link to cytoskeletal proteins

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11
Q

Which cadherins in the spot desmosome junction keep the desmosome together?

A

Desmocolin and desmoglein

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12
Q

What do hemidesmosomes do?

A

They link the cell to the ECM

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13
Q

What is the purpose of the plakin proteins?

A

help distribute stress

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14
Q

Which proteins allow the integral proteins to stay in place?

A

Desmoglobin and plakoglobin

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15
Q

The hemidesmosomes link ____ to _____

A

cell to ECM

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16
Q

Hemidesmosomes are closely related to _____

A

integrins

17
Q

Hemidesmosomes use ____ and _____

A

integrins and plakin protein

18
Q

The hemidesmosome link fibers through the ________ then the ______ and then ______ to the ______

A

plasma membrane then integrin then plakin protein and to the tonofilaments

19
Q

Define: disintegrins

A

enzymes that breakdown integrins found in venom

20
Q

Which desmosome is linked to actin?

A

belt desmosome

21
Q

Belt desmosome give the cell the ability to ____ and gives _______

A

move; lateral stability

22
Q

Belt desmosomes link the ___________

A

periphery of one cell to the periphery of another

23
Q

A connexon is…

A

6 connexins

24
Q

A gap junction causes a

A

1.5 nm channel where water and protons and calcium can move through

25
Q

Gap junctions can…

A

open and close by twisting

26
Q

DEFINE: OCCLUDING JUNCTION

A

it prevents movements through the ECM allowing the cells to have a top and bottom

27
Q

The tight junction ____ the ECM

A

closes

28
Q

Define: tight junction

A

the tight junction allows the things in tissue to stay in

29
Q

Can large molecules move through plant cells?

A

Yes

Biology 411 (20 decks)

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