Endocrinology Flashcards

1
Q

What is the most common cause of cushion’s syndrome in a person > 60?

A

Ectopic ACTH production from small cell lung cancer

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2
Q

Is the PAC:PRA ratio low or high with primary aldosteronism? Secondary aldosteronism?

A

Primary - high (because renin is low)

Secondary like RAS or fibromuscular dysplasia - low (because renin is high)

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3
Q

Are FSH/LH increased or decreased in premature ovarian failure and menopause?

A

Increased due to loss of negative feedback from estrogen

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4
Q

What rash is insulin resistance associated with?

A

Acanthosis nigricans

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5
Q

What is the most common cause of exogenous ACTH production in a patient > 60?

A

small cell lung cancer

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6
Q

How does an adrenal tumor present in terms of cortisol and ACTH?

A

high cortisol and low ACTH

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7
Q

How does adrenal hyperplasia present in terms of cortisol and ACTH?

A

high cortisol and low ACTH

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8
Q

How does Cushing disease (pituitary adenoma) present in terms of cortisol and ACTH?

A

high cortisol and high ACTH

- suppresses with high dose dex test

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9
Q

How does an ectopic ACTH-secreting tumor present in terms of cortisol and ACTH?

A

high cortisol and high ACTH

- fails to suppress with a high dose dex test

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10
Q

What is the relationship between thyroid disease and the prolactin levels?

A

Hypothyroidism causes hyperprolactinemia. Don’t diagnose a prolactinoma until you’ve looked at the thyroid first.

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