Dermatology Flashcards
seborrheic dermatitis is common in patients with what diseases?
HIV/AIDS and Parkinson’s dz
What drug do you not want to mix with oral isotretinoin? Why?
tetracycline antibiotics because you can end up with pseudotumor cerebri
What are the 4 D’s of pellagra?
Pellagra is due to niacin deficiency
The 4 D’s are: photosensitive dermatitis, diarrhea, dementia, and death
What is DRESS and what do you see with it? What drugs are the most common drugs implicated?
drug reaction with eosinophilia and systemic symptoms; you see a morbilliform rash, facial swelling, fever, lymphadenopathy, elevated LFTs, and hepatomegaly. Most cases have associated eosinophilia.
- Anticonvulsants and allopurinol
What bacteria is a known trigger of guttate psoriasis?
strep pharyngitis
What kind of bad side effects can methotrexate cause?
severe liver and pulmonary toxicity and bone marrow suppression; don’t give to patients with h/o etoh abuse, liver disease, or severe kidney impairment
How is the lupus rash on the hands different from the rash of dermatomyositis?
With lupus the rash spares the knuckles but is found on the backs of the hands and between the joint spaces of the fingers; with dermatomyositis the rash if over the knuckles but spares the spaces between
What is the most common nonspecific skin lesion seen in sarcoid?
Erythema nodosum - sarcoid is one of the most common causes; don’t biopsy b/c it won’t show granulomas
If you see Gottron papules, what disease should you consider?
Dermatomyositis
In older patients, dermatomyositis may be a _______ phenomenon.
paraneoplastic
What derm findings do you see with each of these stages of syphilis? Primary, Secondary, and Tertiary?
Primary - chancre - painless
Secondary - diffuse scaling papules on the palms and soles, trunk, penis, and mucosal surfaces; also see condyloma lata
Tertiary - gummas - painless
What’s a characteristic rash seen in Lyme disease?
Erythema migrans
A patient presents with high fever and painful red plaques on the upper extremities, trunk, neck, and face. A skin biopsy shows a dense, but benign neutrophilic infiltrate. What do they have?
SWEET syndrome
Which diseases lead to nikolsky’s signs? Which doesn’t?
Does - SSSS, pemphigus vulgaris, TEN
Doesn’t - bullous pemphigoid
What polyglandular autoimmune syndromes should you think of when you see a pt with vitiligo?
DM, autoimmune thyroid dz, addison dz/adrenal insufficiency, hypoparathyroidism, and pernicious anemia
Malignant acanthuses nigricans is usually associated with what cancer?
gastric adenocarcinoma
Oral hairy leukoplakia is associated with what virus?
EBV in immunocompromised HIV patients
Molluschi contagiosum is frequently seen in HIV/AIDS patients. What other type of infection are they prone to that mimics this?
disseminated cryptococcus infections
A person with HCV presents with a photosensitive rash. What should you think of?
porphyria cutanea tarda
True/False - nystatin is effective against dermatophytes
False
What are a couple of common infections that lead to erythema multiforme?
HSV and mycoplasma
Dermatitis herpetiformis occurs in the context of what disease?
Celiac dz
Guttate psoriasis is usually triggered by?
A strep infection - group A
What class of anti-hypertensive meds should be avoided in stable psoriasis because they make it worse?
beta blockers
Spaghetti and meatballs
“spaghetti and meatballs” of tinea versicolor, also known as pityriasis versicolor. The causative organism, Malassezia furfur, is lipophilic yeast commonly found on the skin. Clinical findings in tinea versicolor are round and oval hyper- or hypopigmented macules and patches with fine scale. The eruption is usually minimally symptomatic.
Christmas tree pattern
pityriasis rosea
