Dermatology Flashcards
seborrheic dermatitis is common in patients with what diseases?
HIV/AIDS and Parkinson’s dz
What drug do you not want to mix with oral isotretinoin? Why?
tetracycline antibiotics because you can end up with pseudotumor cerebri
What are the 4 D’s of pellagra?
Pellagra is due to niacin deficiency
The 4 D’s are: photosensitive dermatitis, diarrhea, dementia, and death
What is DRESS and what do you see with it? What drugs are the most common drugs implicated?
drug reaction with eosinophilia and systemic symptoms; you see a morbilliform rash, facial swelling, fever, lymphadenopathy, elevated LFTs, and hepatomegaly. Most cases have associated eosinophilia.
- Anticonvulsants and allopurinol
What bacteria is a known trigger of guttate psoriasis?
strep pharyngitis
What kind of bad side effects can methotrexate cause?
severe liver and pulmonary toxicity and bone marrow suppression; don’t give to patients with h/o etoh abuse, liver disease, or severe kidney impairment
How is the lupus rash on the hands different from the rash of dermatomyositis?
With lupus the rash spares the knuckles but is found on the backs of the hands and between the joint spaces of the fingers; with dermatomyositis the rash if over the knuckles but spares the spaces between
What is the most common nonspecific skin lesion seen in sarcoid?
Erythema nodosum - sarcoid is one of the most common causes; don’t biopsy b/c it won’t show granulomas
If you see Gottron papules, what disease should you consider?
Dermatomyositis
In older patients, dermatomyositis may be a _______ phenomenon.
paraneoplastic
What derm findings do you see with each of these stages of syphilis? Primary, Secondary, and Tertiary?
Primary - chancre - painless
Secondary - diffuse scaling papules on the palms and soles, trunk, penis, and mucosal surfaces; also see condyloma lata
Tertiary - gummas - painless
What’s a characteristic rash seen in Lyme disease?
Erythema migrans
A patient presents with high fever and painful red plaques on the upper extremities, trunk, neck, and face. A skin biopsy shows a dense, but benign neutrophilic infiltrate. What do they have?
SWEET syndrome
Which diseases lead to nikolsky’s signs? Which doesn’t?
Does - SSSS, pemphigus vulgaris, TEN
Doesn’t - bullous pemphigoid
What polyglandular autoimmune syndromes should you think of when you see a pt with vitiligo?
DM, autoimmune thyroid dz, addison dz/adrenal insufficiency, hypoparathyroidism, and pernicious anemia