Endocrinology Flashcards
endocrinology
study of homeostatic chemical adjustments and other activities that hormones accomplish
hydrophilic hormones
peptide hormones, catecholamines, and indoleamines
lipophilic hormones
steroid hormones, thyroid hormones
peptide hormones
most abundant, chains of amino acids of varying length
catecholamines
produced by the adrenal medulla, are derived from the amino acid tyrosine
indoleamines
produced by the pineal gland, are derived from the amino acid trytophan
steroid hormones
produced by the adrenal cortex and reproductive endocrine glands, neutral lipids derived from cholesterol
thyroid hormones
produced by the thyroid gland, an iodinated tyrosine derivative
hydrophilic hormones primary act through what type of mechanism?
second-messenger systems
lipophilic hormones primarily act through what type of mechanism?
activate genes on binding with receptors inside the cell
where are hydrophilic proteins usually found?
circulate in blood largely dissolved in plasma
GH
growth hormone, stomatotrophin
TSH
thyroid-stimulating hormone, thyrotropin
ACTH
adrenocorticotropic hormone, adrenocorticotrophin
FSH
follicle-stimulating hormone
LH
lutenizing hormone
PRL
prolactin
MSH
melanocyte-stimulating hormone
what are the major functions of ADH?
- via cAMP, it increases aquaporins in the distal convoluted tubule
- causes vasoconstriction in the smooth muscles throughout the body
what are the major functions of OXY?
oxytocin
1. uterine contractions
2. ejection of milk from the mammary glands
3. synthetic pitocin drip can induce labor
what are the major functions of GH?
- fetal growth, cild, puberty
- bone development, soft tissue development
- IGF I and III (idk what this is)
what are the major functions of ACTH?
- growth of the adrenal cortex
what are the major functions of FSH?
- ovarian follicles in women
- increased estrogen production
- sperm production in males
what are the major functions of LH?
- ovulation in women
- increased estrogen and progesterone in women
- increased testosterone from interstitial cells (ICSH)
what are the major functions of PRL?
- breast development in women
- milk production in women
- receptors for LH in the testes
major functions of MSH?
- melanin dispearson
- learning and memory
hormones released by the posterior pituitary (2)
ADH, oxytocin (OXY)
hormones released by the anterior pituitary (7)
GH, ACTH, FSH, LH, TSH, PRL, MSH
which pathway does ADH use for delivery?
cAMP
which pathway does OXY use for delivery?
IP3
which pathway does GH use for delivery?
IP3
which pathway does ACTH use for delivery?
cAMP
which pathway does FSH use for delivery?
cAMP
what pathway does LH use for delivery?
cAMP
which pathway does TSH use for delivery?
cAMP
which pathway does MSH use for delivery?
cAMP
hormone 1
releasing or inhibiting hormone
hormone 2
one of the 6 hormones of the anterior pituitary
hormone 3
targets specific endocrine gland for release
hormone 2 has a short negative feedback loop to…
the hypothalamus
hormone 3 has negative long feedback loops to…
- the anterior pituitary
- the hypothalamus
the gonadotropins
FSH, LH, and maybe PRL (hard to tell on the paper)
where does GH act on the body?
adipose tissue, bone, muscle
where does TSH act on the body?
thyroid
where does ACTH act on the body?
adrenal cortex
where do FSH and LH act on the body?
gonads
where does PRL act on the body?
mamary glands
where does MSH act on the body?
skin cells and the hippocampus
where are ADH and OXY produced?
the supraoptic and paraventricular nuclei
the hypothalamus has two well defined cell clusters, what are they called?
- supraoptic nucleus
- paraventricular nucleus
ADH is also know as….
vasopressin
infundibulum
the connection between the hypothalamus and pituitary glands
- nerve fibers
- bloody vessels
what type of gland is the pineal? mixed or solely endocrine?
mixed
what type of gland is the hypothalamus? mixed or solely endocrine?
mixed
what type of gland is the pituitary? mixed or solely endocrine?
solely endocrine
what type of gland is the thyroid? mixed or solely endocrine?
solely endocrine
what type of gland is the parathyroid? mixed or solely endocrine?
solely endocrine
what type of gland is the thymus? mixed or solely endocrine?
mixed
what type of gland is the heart? mixed or solely endocrine?
mixed
what type of gland is the liver? mixed or solely endocrine?
mixed
what type of gland is the stomach? mixed or solely endocrine?
mixed
what type of gland is the adrenal gland? mixed or solely endocrine?
solely endocrine
what type of gland is the pancreas? mixed or solely endocrine?
mixed
what type of gland is the duodenum? mixed or solely endocrine?
mixed
what type of gland is the kidney? mixed or solely endocrine?
mixed
what type of gland is the adipose tissue? mixed or solely endocrine?
mixed
what type of gland is the skin? mixed or solely endocrine?
mixed
what type of gland is the ovaries? mixed or solely endocrine?
mixed
what type of gland is the placenta? mixed or solely endocrine?
mixed