Endocrinology Flashcards
Chemical substance that is produced by a ductless gland, released into the blood stream, carried to other parts of the body, and produces a specific regulatory effect
Hormone
Two ways that hormones can effect the body
Endocrine route and exocrine route
Hormone will be transported via the blood stream to a target organ
Endocrine route
Hormone is secreted into ducts then travels outside the body where it interacts with a target organ
Exocrine route
Hormone is secreted into space between cells, interstitial fluid carries it to target organ
Paracrine route
Hormones can be grouped based on three chemical structures
Peptides (protein), amines (modifications of tyrosine), steroids (cholesterol)
Which hormones are stored in secretory granules by endocrine cells
Peptide and amines
Which hormone cannot be stored and must be synthesized
Steroid
Three hormones that are not secreted by endocrine glands
Gastric, secretin, erythropoietin
Gastrin release site and function
Wall of the stomach; stimulates release of gastric fluids from gastric glands
Secretin release site and function
Wall of the small intestine; stimulates secretion of intestinal/pancreatic juices
Erythropoietin release site and function
Kidney; stimulates bone marrow
Target organ definition
Identifies the tissue whose cells will be affected by a hormone
Receptor definition; 2 locations
Complex protein structure that allows a hormone to bind to elicit its effects; cell membrane, nucleus
Up-regulation definition
An increase in the number of receptors
Down-regulation definition
A decrease in the number of receptors
The 4 glands that’s function is to produce hormones
Pituitary gland, thyroid gland, parathyroid gland, adrenal gland
Hypothalamus function with hormones
Releases hormones that will stimulate the release of other hormones from the adenohypophysis
Four hormones that are released by the hypothalamus
CRH, GnRH, GHRH, TRH
Which two hormones are produced by the hypothalamus but are stored and released by the neurohypophysis
Oxytocin and anti diuretic
Pituitary gland function with hormones
Contains hormones that will affect the function of organs