Endocrinology Flashcards

1
Q

Chemical substance that is produced by a ductless gland, released into the blood stream, carried to other parts of the body, and produces a specific regulatory effect

A

Hormone

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2
Q

Two ways that hormones can effect the body

A

Endocrine route and exocrine route

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3
Q

Hormone will be transported via the blood stream to a target organ

A

Endocrine route

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4
Q

Hormone is secreted into ducts then travels outside the body where it interacts with a target organ

A

Exocrine route

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5
Q

Hormone is secreted into space between cells, interstitial fluid carries it to target organ

A

Paracrine route

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6
Q

Hormones can be grouped based on three chemical structures

A

Peptides (protein), amines (modifications of tyrosine), steroids (cholesterol)

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7
Q

Which hormones are stored in secretory granules by endocrine cells

A

Peptide and amines

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8
Q

Which hormone cannot be stored and must be synthesized

A

Steroid

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9
Q

Three hormones that are not secreted by endocrine glands

A

Gastric, secretin, erythropoietin

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10
Q

Gastrin release site and function

A

Wall of the stomach; stimulates release of gastric fluids from gastric glands

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11
Q

Secretin release site and function

A

Wall of the small intestine; stimulates secretion of intestinal/pancreatic juices

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12
Q

Erythropoietin release site and function

A

Kidney; stimulates bone marrow

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13
Q

Target organ definition

A

Identifies the tissue whose cells will be affected by a hormone

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14
Q

Receptor definition; 2 locations

A

Complex protein structure that allows a hormone to bind to elicit its effects; cell membrane, nucleus

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15
Q

Up-regulation definition

A

An increase in the number of receptors

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16
Q

Down-regulation definition

A

A decrease in the number of receptors

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17
Q

The 4 glands that’s function is to produce hormones

A

Pituitary gland, thyroid gland, parathyroid gland, adrenal gland

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18
Q

Hypothalamus function with hormones

A

Releases hormones that will stimulate the release of other hormones from the adenohypophysis

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19
Q

Four hormones that are released by the hypothalamus

A

CRH, GnRH, GHRH, TRH

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20
Q

Which two hormones are produced by the hypothalamus but are stored and released by the neurohypophysis

A

Oxytocin and anti diuretic

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21
Q

Pituitary gland function with hormones

A

Contains hormones that will affect the function of organs

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22
Q

The pituitary gland is made up of two different types of tissue

A

Epithelial and nervous tissue

23
Q

The anterior pituitary produces 6 hormones

A

ACTH, FSH, LH, GH, TSH, PRL

24
Q

The posterior pituitary doesn’t produce hormones but stores and releases two hormones

A

Oxytocin and ADH

25
ACTH function
Stimulates release of hormones from adrenal gland, contains corticosteroids (fight or flight response)
26
LH and FSH function
Regulation of male and female reproductive processes
27
GH function
Stimulates changes in target organs that support growth
28
ADH function
Kidney function
29
Oxytocin function
Smooth muscle contraction
30
The thyroid gland secrets 3 hormones
T4 (Thyroxine), T3 (Triiodothyronine), Calcitonin
31
T3 function
Increases basal metabolic rate
32
Calcitonin function
Helps control calcium levels; acts to decrease blood calcium by inhibiting osteoclasts
33
What hormone does the parathyroid secret
PTH
34
PTH function
Increases blood calcium and lowers blood phosphorus; stimulates release of calcium and phosphorus from bone by +cites and blasts
35
The Adrenal Cortex produces which two hormones
Glucocorticoids and Mineralocorticoids
36
The Adrenal Medulla produces
Catecholamines
37
Glucocorticoids function
Enhances production of glucose
38
Mineralocorticoids function
Regulates sodium and potassium levels in the blood
39
Catecholamines function
Fight or flight response
40
Three main hormones of the pancreas
Insulin, glucagon, somatostatin
41
Insulin function
Decrease blood glucose
42
Glucagon function
Increases blood glucose
43
Somatostatin function
slows the mobilization and production of nutrients
44
When glucose is released into the bloodstream, this causes the blood glucose concentration to ____
Rise
45
Where is extra glucose stored and what as
In the liver; Glycogen
46
What happens when the blood sugar concentration drops
Glucagon releases Glycogen, glycogenesis
47
Type 1 diabetes
Pancreas is unable to produce insulin
48
Type 2 diabetes
Insulin insensitivity
49
Cells of the penal gland that are secretory and supported by neuroglia and receives input from axons
Pinealocytes
50
Pinealocytes function
Produces enzyme that converts serotonin into melatonin
51
Hormones are regulated by two methods
Negative and positive feedback
52
Negative feedback regulation
Rising levels of hormone = biologic response to further release blood glucose levels
53
Positive feedback regulation
Hormones cause a biologic response, producing an increase in the release of the hormone