Endocrine System and Diabetes Flashcards

1
Q

Negative feedback system

A

Return to a set point

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2
Q

Positive feedback system

A

Reach a specific point

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3
Q

Hormone

A

Chemical messenger
Stimulate or inhibit a receptor or function
Maintain homeostasis
Secretes into the blood

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4
Q

Endocrien hormone

A

Can effect any cell in the body

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5
Q

Hormones cause effect only on..?

A

cells with a matching receptor

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6
Q

How does a hormone cause effect?

A

binding with receptor either inside or outside the cell

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7
Q

2 organs that regulate glucose in the blood

A

Liver, and pancreas

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8
Q

Where are the islets of langerhans

A

pancreas

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9
Q

2 functions of the islets

A
enzyme production that aids in digestion 
Make insulin (alpha and beta cells)
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10
Q

Alpha cells

A

Secrete hormone to produce glucose

Hormone: glucagon

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11
Q

Beta cells

A

Secrete hormone to tell cells to store glucose

Hormone: insulin

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12
Q

Where will overflow of glycogen get stored

A

adipose (fat) cells

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13
Q

Insulin life-span

A

After binding is degrades
Not used than kidneys and liver will destroy it
Has half-lives (dies quickly)

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14
Q

Adipose cells

A

Functions like an endocrine gland or tissue

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15
Q

2 types of adipose cells

A

Subcutaneous and visceral

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16
Q

3 ways to assess visceral fat

A

BMI, waist circumference, and waist to hip ratio

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17
Q

Insulin resistance

A

Target cell’s receptors are unresponsive to insulin
Too much insulin in blood
Hungry and tired

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18
Q

2 tests to see if someone is hyperglycemic

A

FGP (fasting plasma glucose)

2hPG (Two hour plasma glucose)

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19
Q

Normal blood glucose

A

between 4.4 - 5 mmoL/L

20
Q

Metabolic syndrome

A

Group of symptoms that make you have a higher risk for heart disease and type 2 diabetes

21
Q

Type 1 diabetes

A

insulin is insufficient in amount
Pancreatic cell destruction
Acute onset
Autoimmune or idiopathic

22
Q

Risk factors for type 1

A

Genes (1st degree relative)

23
Q

What is happening to insulin in type 1

A

it’s being destroyed or is not being produced

24
Q

Treatment for type 1

A

synthetic insulin

25
Complications in type one
Amputations, blindness, neuropathy, retinopathy
26
Ongoing monitoring in type 1
dehydration, glucose levels, exercise, hot and cold
27
Type 2
Insulin is insufficient in action Insulin resistance Gradual onset
28
Risk factors in type 2
``` Obesity Smoking Age Sedentary lifestyle Race ```
29
Treatment with type 2
Regulate diet and exercise | Pill that changes how cells respond to sugar
30
Complications with type 2
Same as type 1 plus insulin dependance
31
Glucosuria
Glucose in pee
32
Polydipsia/dehydration
Drinking water all the time
33
Polyuria
Peeing all the time
34
Blurred vision
High BS changes the shape of the eye
35
Weight loss
Can't break down glucose fro energy so it breaks down fat
36
Fatigue
cells are hungry because they aren't getting the glucose they need
37
Polyphagia
Always hungry and eating
38
2 types of vascular damage with hyperglycemia
macro (large blood vessels) | Micro (small blood vessels)
39
3 major components to manage diabetes
food exercise and glucose
40
Insulin dependant
type 2 when pancreas stops functioning all together | Also new diagnosed type 2
41
Hypoglycemia
low BS | too much insulin
42
How does hypoglycemia happen
failing to eat and too much exercise | Too much insulin injected or stressed out
43
Another name for severe hyperglycemia
diabetes ketoacidosis
44
Hyperglycemia
increased BS | Low insulin levels
45
How does hyperglycemia happen
Miss medication, stress, other meds
46
Post prandial
after a meal