Endocrine System Flashcards
Endocrine
Releases substances (hormones) into the bloodstream
Exocrine
Releases substances to outside of body or into intestines
Example of an exocrine gland
One that secretes digestive enzymes
Hypothalamus
The “control center” for pituitary gland
What does the hypothalamus produce?
Releasing factors
What do releasing factors from the hypothalamus do?
Stimulate the pituitary to produce hormones
What are the two parts of the pituitary gland?
Anterior and posterior pituitary
Adenohypophysis
Anterior pituitary
Glandular tissue
Neurohypophysis
Posterior pituitary
Neural tissue
Extension of the hypothalamus
What does the pituitary gland do?
Releases hormones
Where is ACTH produced?
Anterior pituitary
Where is GH produced?
Anterior pituitary
Where is MSH produced?
Anterior pituitary
Where is TSH produced?
Anterior pituitary
Where is FSH and LH produced?
Anterior pituitary
Where is prolactin produced?
Anterior pituitary
Where is oxytocin produced?
Posterior pituitary
Where is ADH produced?
Posterior pituitary
Target Organs
Cells on organs that have receptors for specific hormones
Target organs for oxytocin
Uterus Mammary glands (breasts)
Functions of oxytocin
Stimulates contractions in the uterus
Promotes milk SECRETION in mammary glands
Disorders of oxytocin
Unknown
Target organs for prolactin
Mammary glands (breasts)
Functions of prolactin
Promotes milk PRODUCTION
Hyposecretion of prolactin results in
Decreased milk production in nursing mothers
Galactorrhea
Abnormal milk production
Excess milk production in non-nursing women or men
Target organs for follicle-stimulating and luteinizing hormones
Ovaries
Testes
Functions of follicle-stimulating and luteinizing hormones in females (2)
Promotes egg production and ovulation
Stimulates estrogen and progesterone production
Functions of follicle-stimulating and luteinizing hormones in males (2)
Promotes sperm production
Stimulates testosterone production
Hyposecretion of follicle-stimulating and luteinizing hormones
Decreased reproductive capacity
Hypersecretion of follicle-stimulating and luteinizing hormones
Unknown
Thyroid Hormones
Calcitonin
T4 and T3
Calcitonin
Thyroid hormone
Decreases blood calcium levels
How does calcitonin decrease blood calcium levels?
Takes calcium out of blood to build bones
Increases calcium loss from kidneys
What do T4 and T3 do?
Regulate metabolism
Myxedema
Slow metabolism
Hypothyroidism
Hyposecretion of TSH
Symptoms of myxedema (4)
Cold
Overweight
Fatigue
Swelling of face
Grave’s Disease
Increased metabolism
Hyperthyroidism
Hypersecretion of TSH
Symptoms of Grave’s Disease (4)
Low weight
Heart arrhythmia
Anxiety
Exopthalamus
Exopthalamus
Bulging eyes
What causes exopthalamus?
Tissues are built up/swell behind eyes to push them out, causing them to bulge
Target organs for growth hormones (4)
Bones
Cartilage
Liver
Muscles
Functions for growth hormones (2)
Stimulates growth
Increases use of fats for energy
Pituitary Dwarfism
Hyposecretion of growth hormones in children
Gigantism
Hypersecretion of growth hormones in children
Acromegaly
Enlargement of extremities
Hypersection of growth hormones in adults
What else can acromegaly influence?
Organs
What almost always causes gigantism and acromegaly?
Pituitary tumor
Target organs for adrenocorticotropic hormone
Adrenal Cortex
Functions of adrenocorticotropic hormone (2)
Stimules cortisol secretion
Helps body handle stressful situations
Cortisol
Stress hormone
Cushing Disease
Hypersecretion of cortisol (from adrenocorticotropic hormone)
Fat distribution is altered
Symptoms of Cushing Disease
Weight gain Hair loss Slow healing Moon face Buffalo hump
Target organs for antidiuretic hormones (like vasopressin)
Kidneys
Function of antidiuretic hormones
Stimulates the increase in water reabsorption in nephrons
Diabetes Insipidus
Hyposecretion of antidiuretic hormone
Symptoms of diabetes insipidus
Excess urine production
Dehydration
Electrolyte (salt) imbalances
Non-Pituitary Hormones (13)
Calcitonin Thyroxine Triiodothyronine Parathyroid Hormone Glucocorticoids (cortisol) Mineral Corticoids (aldosterone) Epinephrine Norepinephrine Glucagon Insulin Estrogen Testosterone Melatonin
Where is the pineal gland located?
In brain
What does the pineal gland produce?
Melatonin
Melatonin
Helps regulate daily cycles
Where is thymus located?
Behind sternum
Looks like a butterfly
What does the thymus do?
Helps develop immune systems in children
Adrenal Gland Hormones (2)
Mineral corticoids
Glucocorticoids
Mineral Corticoids
Increases blood sodium levels
Hold more sodium in body
How do mineral corticoids increase blood sodium levels?
Increasing reabsorption by kidneys
What produces mineral corticoids?
Adrenal cortex
Aldosteronism
Hypersecretion of mineral corticoids
Increases blood pressure and lowers potassium levels
Addison’s Disease
Hyposecretion of mineral corticoids
Symptoms of Addison’s disease (4)
Fatigue
Dizziness
Low blood pressure
Darkened skin
Who had Addison’s disease?
JFK
Glucocorticoids (2)
Regulate metabolism of carbs, proteins, and fats
Decreases inflammation
What produces glucocorticoids?
Adrenal cortex
What results from a hypersecretion of glucocorticoids?
Cushing Disease
Parathyroid Hormones
Opposite of calcitonin
Increases blood calcium levels
How do parathyroid hormones increase blood calcium levels?
Breaks down bone to get the calcium
Increases reabsorption by kidneys
Pancreatic Hormones (2)
Glucagon
Insulin
Glucagon
Increases blood glucose
How does glucagon increase blood glucose?
Stimulating breakdown of glycogen
Glycogen
Storage form of glucose
Where is glycogen?
Liver and muscles
Hypoglycemia
Low blood sugar
Hyposecretion of glucagon
Insulin
Decreases blood glucose
How does insulin decrease blood glucose?
Stimulating cells to take up glucose from the blood
What is Diabetes Mellitus Type 1 caused by?
Not enough insulin in body
Hyposecretion of insulin from the pancreas
What happens during Diabetes Mellitus Type 1?
Body cannot absorb glucose
An autoimmune process where body attacks the insulin-producing cells
Hyperglycemia
High blood glucose
What is Diabetes Mellitus Type 2 caused by?
Cells in body not responding to insulin
Poor food choices and genetics
What happens during Diabetes Mellitus Type 2?
Plenty of insulin is produced, but cells don’t act as they should
Causes hyperglycemia
Symptoms of diabetes mellitus
Polydipsia
Polyuria
Polyphagia
Polydipsia
Excessive thirst
Polyuria
Excessive urination
Polyphagia
Excessive eating
Why is polydipsia a symptom of diabetes mellitus?
Person is losing a lot of water in urine
Why is polyuria a symptom of diabetes mellitus?
Glucose in urine “pulls” water with it into urine so less water gets reabsorbed by kidneys
Why is polyphasic a symptom of diabetes mellitus?
Person is not able to utilize glucose effectively in body, so they are always hungry