Endocrine System 1 Flashcards
What are the 3 types of Hormones?
Steroids, Amines, Proteins/Polypeptides
______ are made from lipids and cholesterol
Steroids
Aldosterone & cortisol are made by?
Adrenal cortex
______ are derived from tyrosine
Amines
______ are hormones made from less than 100 amino acids
Polypeptides
______ are hormones made from more than 100 amino acids
Proteins
______ hormones can go directly into the cell via cytoplasmic or nuclear receptors
Hydrophobic
______ hormones cannot enter the target tissue and need to combine with receptor on cell membrane
Hydrophilic, activates 2nd messenger system
All hormones are transported in the ______
Blood
Steroid hormones bind to ______ receptors and increase _____________
Cytoplasmic, increase protein synthesis by mitochondria & ribosomes
Thyroid hormones bind to ______ receptors and increase _______________
Nuclear, increase gene transcription in the cell nucleus
All other hormones bind to _______ receptors
Cell membrane
Through this 2nd messenger system, G protein activates adenylate cyclase & ATP -> cAMP -> activates protein kinase
cAMP system
Through this 2nd messenger system, G protein activates phospholipase, which activates DAG -> activates protein kinase
DAG system
Through this 2nd messenger system, G protein activates phospholipase, which activates DAG, which activates IP3 -> activates IP3-gated Ca2+ channel or releases Ca2+ from ER, or both! Buildup of Ca2+ activates intracellular enzyme (other effect) or calmodulin -> activates protein kinase
IP3 system