Endocrine Part 5 Fluid Balance Miliotis Flashcards

1
Q

How is water distributed in the body?

A

About 2/3 is in the intracellular fluid, and 1/3 is in the extracellular fluid (includes interstitial fluid and plasma)

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2
Q

how much of the body is made of water?

A

The body is 55% water.

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3
Q

What are the main sources of water intake in the body? (3)

A

Food, drinks, metabolic processes.

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4
Q

What are the main sources of water loss in the body? USLF

A

Urine, skin, lungs, feces.

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5
Q

What happens if the body has too much water loss?

A

Dehydration

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5
Q

What happens if the body has too much water retention?

A

cause swelling and other health issues.

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6
Q

What are the steps involved in urine formation? (3) FRS

A

Filtration, Reabsorption, Secretion

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7
Q

what is the filtration step in urine formation?

A

Blood plasma is filtered in nephrons.

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8
Q

what is the reabsorption step in urine formation?

A

Water and necessary substances are reabsorbed.

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9
Q

what is the secretion step in urine formation?

A

Waste and excess substances are secreted.

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10
Q

What are the main parts of the nephron?

A

Proximal Tubule, Loop of Henle, Collecting Duct

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11
Q

what is the job of the Loop of Henle?

A

Reabsorption of water and electrolytes

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12
Q

what is the job of the Proximal Tubule?

A

Filtration

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13
Q

what is the job of the Collecting Duct?

A

Final water reabsorption

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14
Q

What hormones regulate fluid balance in the body? (3)

A

Vasopressin (ADH), Aldosterone, ANP

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15
Q

What is Vasopressin’s job (water reabsoprtion, blood pressure, fluid retention)? (3)

A

Increases water reabsorption, Increases blood pressure and increases fluid retention.

16
Q

what is the job of Aldosterone (Na and water reabsorption, blood pressure, fluid retention)? (3)

A

Increases sodium and water reabsorption, Increases BP, increases fluid retention

17
Q

what is the job of ANP (water reabsoprtion, urine production, blood pressure, fluid retention)? (4)

A

Decreases water reabsorption, and increases urine production, decreases blood pressure, decreases fluid retention.

18
Q

What is the main function of Antidiuretic Hormone (ADH) and what is the significance of this (water reabsoption, blood volume and pressure)?

A

ADH increases water reabsorption in the kidneys, raising blood volume and pressure.

19
Q

Where is ADH synthesized?

A

hypothalamus

20
Q

Where is ADH secreted from?

A

Posterior Pituitary

21
Q

What stimulates ADH release? (2)

A

High plasma osmolarity.

Low blood pressure (secondary stimulus)

22
Q

What specifically does Aldosterone do? (2)

A

Reabsorbs sodium in the distal tubule and collecting duct.

Secretes potassium.

23
Q

What triggers the renin-angiotensin pathway and what hormone does it release?

A

Low blood pressure triggers the release of renin

24
Q

What organs are Natriuretic Peptides secreted from?

A

heart, lungs, and brain

24
Q

what does the release of renin lead to the production of and what is the significance of this?

A

which leads to angiotensin II production, increasing thirst and causing aldosterone secretion to raise blood pressure

25
Q

What are Natriuretic Peptides?

A

They are vasodilators and diuretics

25
Q

What is the job of Natriuretic Peptides (sodium reabsoprtion, blood pressure)?

A

decrease sodium reabsorption and blood pressure

26
Q

How much urine is excreted daily?

A

About 1.8 L of urine is excreted daily from 180 L of filtrate formed.