Endocrine Disorder Flashcards
What is the endocrine system composed of?
glands, tissues, or clusters of cells that produce and release hormones
What is the gold standard for making the diagnosis of GH excess?
Failure to suppress serum GH levels after an oral glucose challenge test
Lab/Diagnostic Studies for Diabetes Insipidus
- Radiographic studies
- Urinalysis
- Serum Osmolarity
- Serum Sodium
- Fluid Deprivation
What are the two types of pituitary disorders?
Anterior and Posterior
Anterior Pituitary Disorders
- Growth Hormone Deficiency
- Hyperpituitarism
- Precocious Puberty
Posterior Pituitary Disorders
- Diabetes Insipidus
- Syndrome of Inappropriate Antidiuretic Hormone Secretion
When is Growth Hormone typically released?
-throughout the day, mostly secreted during sleep
What is growth hormone deficiency usually a result of?
Failure of the anterior pituitary or hypothalamic stimulation on the pituitary to produce sufficient GH
GH Deficiency is also known as what?
Hypopituitarism or Dwarfism
What is GH Deficiency characterized by?
poor growth and short stature
Complications for GH Deficiency Include?
unable to metabolize protein, fat, and carbohydrates effectively
What is the primary cause of GH Deficiency?
Injury to pituitary gland or hypothalamus
What may cause injury to the pituitary gland or hypothalamus resulting in GHD?
- tumor
- infection/infarction
- CNS irradiation
- abnormal formation in utero
- birth trauma
- Genetics (Prader-Willi or Turner)
- Psychosocial
Therapeutic Management for GHD
- supplement GH
- removal of tumors
- continue treatment until near final height
- physical exam
What would you see on a Physical Exam for a child w/ GHD?
- height at or < 3rd percentile
- higher weight to height ratio
- prominent abdominal fat
- large forehead
- high pitched voice
- delayed sexual maturity, dentition, skeletal maturation
- decreased muscle mass
Teaching Plan for GHD
- promoting growth
- enhancing the child’s self esteem
- providing appropriate education on disorder
When does treatment stop for GHD?
With fusion of growth plates
How often should you measure a child’s height w/ GHD?
q 3-6 months
What should the child notify the physician about during treatment?
- headaches
- rapid weight gain
- increased thirst/urination
- joint pain
Complications of GHD
- altered carbohydrate, protein, fat metabolism
- hypoglycemia
- glucose intolerance/diabetes
- slipped capital femoral epiphysis
- pseudotumor cerebri
- leukemia
- recurrence of CNS tumors
- Infection at injection site
- edema and sodium retention
Precocious Puberty
Development of sexual characteristics before the usual age of pubertal onset
When does Precocious Puberty begin for boys and girls?
Younger than 8 for girls and 9 for boys