Endocrine and Metabolic Disorders Flashcards
_____________ are organs that manufacture and secrete chemical substances.
Glands
_________________ glands secrete chemicals to the outer surface of the body.
Exocrine
__________ glands secrete chemical hormones into the bloodstream.
Endocrine
The ________________ contains several control centers for body functions and emotions.
hypothalamus
The terms “free T” refer to thyroid hormones that are in circulation but not _____________.
protein bound
Parafollicular cells, which are less numerous than follicular cells, are responsible for secreting _________________ hormone, which controls calcium metabolism.
calcitonin
When you check the patient’s vital signs, look for the combination of hypertension and bradycardia, which suggests increased _____________________.
intercranial pressure
To obtain a positive ____________, place a blood pressure cuff around the arm, inflate it to 30 mmHg above systolic, and hold it in place for 3 minutes.
Trousseau’s Sign
You can elicit a positive _______________ by tapping the facial nerve against the mandibular bone just anterior to the ear, which produces a spasm of the facial muscles.
Chovstek’s Sign
In patients with hypocalcemia, the QT interval is ________________.
prolonged
Graves’ Disease, also known _______________ is the most common form of hyperthyroidism.
diffuse toxic goiter
______________ is an endocrine dysfunction characterized by absent or decreased secretion of thyroid hormones.
Hypothyroidism
When hypothyroidism becomes chronic and extreme, it may evolve into a life-threatening condition called _______________.
myxedema coma
Primary adrenal insufficiency, known as _________________, is a metabolic and endocrine ailment caused by a direct insult to, or malfunction of the adrenal cortex.
Addison’s Disease
____________________ is responsible for keeping serum levels of sodium and potassium in balance.
Aldosterone
_________________________________ is a condition in which the body’s need for glucocorticoids and mineralocorticoids exceeds the delivery of these hormones by the adrenal glands.
Acute Adrenal Insufficiency
When adrenal insufficiency is accompanied by hypotension, the condition is called ____________ and constitutes a true life-threatening emergency.
adrenal crisis
Hyperadrenalism, or ____________, os the clinical condition caused by long-standing exposure to excessive circulating serum levels of glucocorticoids, particularly cortisol.
Cushing’s Disease
____________ diabetes is characterized by being unable to produce any insulin due to pancreatic B-cell destruction.
Type 1
_____ diabetes is characterized by progressive cellular insulin resistance and a gradual failure of pancreatic B-cell insulin production.
Type 2
Th classical clinical manifestations of diabetes is referred to as the 3 P’s:
polydipsia
ployuria
polyphagia
Hypoglycemia in patients who have no history of diabetes is called fasting or ____________ hypoglycemia.
postprandial
___________ is an acute endocrine emergency in which insulin deficiency and an excessive glucagon level combine to create a hyperglycemic, acidotic, volume depleted state.
Diabetic Ketoacidosis
Hyperglycemia pulls fluid into the extracellular space, triggering ____________, which in turn causes hypotension and volume deficit.
osmotic diuresis