Endocrine

Question 1

What test is used to evaluate adrenal insufficiency?

Answer 1

ACTH stimulation test

Question 2

How do you distinguish primary vs secondary hypercortisolism?

Answer 2

dexamethasone suppression test

Question 3

What are the clinical manifestations of hyperaldosteronism?

Answer 3

hypernatremia, hypokalemia, metabolic alkalosis, hypertension, increased urine output

Question 4

What is struma ovarii?

Answer 4

functioning thyroid tissue in an ovarian malignancy

Question 5

What is the mechanism of Propylthiouracil?

Answer 5

inhibits thyroid hormone synthesis and conversion of T4 and T3

Question 6

What is the most lethal clinical sequela of hypothyroidism?

Answer 6

myxedema coma

Question 7

What is MEN I? What is the inheritance pattern?

Answer 7

autosomal dominant

tumors of the parathyroid, pancreas, and pituitary gland

Question 8

What is MEN IIa? What is the inheritance pattern?

Answer 8

autosomal dominant

parathyroid hyperplasia, medullary thyroid cancer, pehochromocytoma

Question 9

What is the medical treatment for pheochromocytoma?

Answer 9

phenoxybenzamine

Question 10

What is MEN IIb?

Answer 10

medullary thyroid cancer, pheochromocytoma, mucosal neuromas, intestinal ganglioneuromas, Marfinoid habitus