Endocrine

Question 1

MDx? What condition is this pathognomonic for?

Answer 1

MDx: calcinosis cutis

Pathognomonic for Cushing’s disease

Question 2

MDx? Etiology? Disease?

Answer 2

MDX: diffuse cortical hyperplasia

Etiology: ACTH secreting pituitary adenoma

Dz: Cushing’s

Question 3

Thyroid from a dog

MDx? What other lesions would you expect to see in this dog? Histological MDx?

Answer 3

MDx: thyroid atrophy

Eyes - mucopurulent conjunctivitis, heart - coronary atherosclerosis

Histological MDx: lymphocytic thyroiditis

Question 4

Thyroid of a cat

MDx? Etiology? What other lesions would you expect to see?

Answer 4

MDx: multifocal thyroid adneomas/hyperplasia

Etiology: hyperthyroidism

Heart - biventricular cardiac hypertrophy and myocardial infarcts

Kidney - renal infarcts

Question 5

Parathyroid from a cat

MDx? What other lesions will you look for?

Answer 5

MDx: multifocal parathryroid hyperplasia

Look for areas of metastatic calcification (kidney, stomach, aorta, lungs)

Question 6

Adrenal gland from the horse

Best diagnosis?

Answer 6

Pheochromocytoma

Question 7

Leg of an iguana

MDx? Etiology? Disease?

Answer 7

MDx: fibrous osteodystrophy

Etiology: renal disease or secondary hyperparathyroidism

Dz: rubber leg

Question 8

Pancrease of a ferret (can’t you tell?)

MDx? Dz? Associated lesions?

Answer 8

MDx: metastatic islet cell carcinoma

Dz: insulinoma

Associated lesion: hyperglycemia