Endocrine Flashcards
Dextrose 50% (D50W)
Class
Carbohydrate
Dextrose 50% (D50W)
Description
Simple sugar that the body can rapidly metabolize to create energy
Dextrose 50% (D50W)
Indication
Hypoglycemia
Dextrose 50% (D50W)
Contraindication
None in hypoglycemia
Avoid in christen less than 2y/o
Dextrose 50% (D50W)
Dosage
Adult:
Pedi:
Glucagon (GlucaGen)
Class
Hormone, Anti-hypoglycemia
Glucagon (GlucaGen)
Description
Protein secreted by pancreatic cells that causes a breakdown of glycogen into glucose
Glucagon (GlucaGen)
Indication
Hypoglycemia without IV access and to reverse beta-blocker and Calcium Channel Blocker overdose
Glucagon (GlucaGen)
Contraindication
None
Glucagon (GlucaGen)
Precaution
Cardiovascular or renal impairment. Effective only if there are sufficient stores of glycogen in the liver
Glucagon (GlucaGen)
Dosage Hypoglycemia
Adult: 1mg IM repeat every 10-20mins
Pedi: 0.1mg/kg IM/SC/IV child < 10kg
Glucagon (GlucaGen)
Dosage Beta-blocker/CCB OD
Adult: 3mg IV over 1 min
Pedi: 50-150 mcg/kg IV over 1 min
Metoclopramide (Reglan)
Class
Antiemetic
Metoclopramide (Reglan)
Description
Dopamine antagonist similar to procainamide but with few antidysrhythmic or anesthetic properties. Its antiemetic properties stem from rapid gastric emptying and desensitization of the vomiting reflex
Metoclopramide (Reglan)
Indication
Nausea and vomiting
Metoclopramide (Reglan)
Contraindication
Hypersensitivity, seizure disorders, GI obstruction or proforation, and breast cancer
Metoclopramide (Reglan)
Precautions
CHF, hypokalemia, renal impairment, GI hemorrhage, intermittent porphyria
Metoclopramide (Reglan)
Dosage
Adult only
5-10mg IV/IO/IM
Avoid with diarrhea
Zofran
Class
Antiemetic
Zofran
Description
Selective blocking agent of the serotonin5-HT3 receptor type
Zofran
Indication
Prevention of nausea and intractable vomiting
Zofran
Contraindication
None
Zofran
Precaution
May mask a progressive ileus and/or gastric distension, Long QT syndrome
Zofran
Adult dose
4mg IVP/IO/IM or single 4mg tablet ODT
