Endocrine Flashcards
Thyroid
Regulates Metabolism so change all thyroids to metabolism
Hyperthyroidism
HyperMeabolism
s/sx:
weight loss
increased HR & BP
Hyperpersonality (inrritable)
Heat intolerance (hyper=hot)
Cold tolerance
exophthalmos (bulging eyes)
Graves Disease: Hyper people run, run themselves into the grave
Hyperthyroid Tx
- Nuke it w/ Radioactive Iodine
2.PTU(propylithouracil)
3.Thyroidectomy (most common)
Radioactive Iodine
-private room/no visitors for first 24 hrs
-flush 3 times after peeing
-Hazmat team called if urine spills
PTU
-PTU: Puts Thyroid Under
-primary use of drug is for cancer so monitor WBC b/c pt is immunosupressed
Thyroidectomy
Total vs Sub/partial
Total:
-lifelong hormone replacement
-risk for hypocalcemia
Sub/partial:
-temp hormone supplement but not lifelong tx
-THYROID STORM RISK: Medical emergency
Thyroid Storm
s/sx:
temp of 105+
High BP, stroke level
severe tachycardia
psychotically delirious
tx: Get body temp down and O2 up
FIRST step is ice pack
BEST step is cooling blanket
Give o2 at 10L
stay with pt
Postop Thyroidectomy risks
first 12 hrs: risk are same for total & sub
-Top priority is AIRWAY b/c of edema
-HEMORRHAGE b/c its a vascular endocrine gland
12-48 hrs: risks are diff for total & sub
-total: TETANY due to low calcium can close of airway with a spasm (total = tetany)
-sub: THYROID STORM (subtotal = storm)
after 48 hrs: risk is infection
Hypothyroidism
Hypometabolism
s/sx:
obesity
decreased HR &BP
Personality: flat/ dull/boring
Cold intolerance
Heat tolerance
Academically challenged
severe case:
myxedema: pt presents with skin involvement
myxedema coma: MED EMERGENCY - slowing of multiple organ functions
Hypothroidism Tx
Levothyroxine (synthroid)
-take in morning 30min-1 hr before breakfast
-take on empty stomach w/ water
NEVER sedate pts theyre already super low
NEVER hold if undergoing surgery b/c w/o it increases anesthesia affects and person will die
Adrenal Cortex Disease
All adrenal cortex disease star with A or C
Addison disease
under secretion of steroids
PERSON IS TICKING TIME BOMB
They cannot adapt to any type of stress and go into SHOCK
s/sx: hyperpigmented (tan)
shock
tx: Steroids (glucocorticoids)
-drugs that end in SONE
IN ADDISON YOU ADD A SONE
Cushings Syndrome
Cushy tushy -> over secretion of steroids
Cushings s/sx
ALL s/sx of cushings are the S/e of steroids
-moon face
-hirstutism: lots of hair
-central/truncal obesity w/ extremity muscle atrophy (really big body with tiny little legs)
-Bump on front & back (gynecomastia:big breast & buffalo hump)
-stretch marks
-easy bruising
-retain water & sodium & looses K (full & salty…K bye)
-mad because they have an infection (roid rage and immunosuppressed
-HIGH SERUM GLUCOSE ; look like diabetics, checks q6h
Cushings Tx
Adrenalectomy
-now has addisons disease so ADD A SONE
-s/e of steroids will result in th s/sx of cushings and will regulate after a year