Endell Flashcards
What is the threshold for somatic cell count which would make you want to treat the cow for subclinical mastitis?
> 200,000 SCC CMT
What are the two types of mastitis?
- environmental
- contagious
What is the test for SCC called?
California Milk Test
Aminoglycosides- broad spec or narrow?
narrow
Aminoglycosides - gram negative or gram positive?
gram negative
What drugs are HP-CIAs?
- fluoroquinolones
- macrolides
- cephalosporins 3rd-4th gen
E. Coli- gram negative or gram positive?
Gram negative
Define metaphylaxis
Treatment given to the entire herd as opposed to the individual
Causes of calf scour
- Rotavirus
- Coronavirus
- Salmonella
- E. Coli
- Cryptococcus
What are the two bacteria that can cause calf scour? (<2 weeks)
- E. Coli (<3days)
- Salmonella
What test can you use on the farm that tests for calf scours?
SNAP test for corona/ rota, crytpo, e.coli
What bacteria does the SNAP test used to detect calf scours NOT account for?
Salmonella (but animals will have bloody faeces and pyrexia)
Pathogens that can cause calf pneumonia?
(<6m)
- Mannheimia hemmolytica
- Mycoplasma Bovis
- IBR- BHV
- (BVD indirectly as it causes immunocompromise)
- Pasteurella Multocida
- Histophilus Somni
- Parainfluenza 3
What are the Bacterial Pathogens that can cause calf pneumonia? Are these commensals or non- commensals?
- Histophilus Somni
- Mannheimia Hemmolytics
- Mycoplasma Bovis
- Pasteurella Multocida
ALL COMMENSALS so usually 2ndary to viral infection- thats why its best to sample in the early stages of disease.
What causes new forest eye?
Moraxella Bovis
How would you treat calf pneumonia?
- oxytetracycline 1st line - then florfenicols—-> macroclides (3rd line)
- NSAIDs ie flunixin
Why use meloxicam instead of flunixin?
- longer acting
What does a bacteriostatic antibacterial require?
a functional immune system
Pencillin factors
- gram positive
- cidal
- time
- poor penetration into CNS
Why can penicillin be used in cases of meningitis?
Because the BBB is damaged during inflammation
Where does penicillin not work?
- acidic environments
- against mycoplasma
- in pus/ necrotic tissue
- not in CNS
Why is amoxyclav better than penicillin G?
- active in pus/necrotic
- is good against gram positive and negative
- inhibits Beta lactamases
What is amoxycillin ineffective against?
- CNS
- mycoplasma (no cell wall)
where does oxytetracycline not get into?
- the uterus
TMPS - broad or narrow spec?
broad spectrum
TMPS- static or cidal?
cidal
TMPS- time or dose dependent?
time-dependent
tetracycline- dose or time dependent?
time-dependent
Example of an antibiotic has 0 milk withdrawal period?
Cephalophorins - 1 to 4??
Which NSAID has 0 milk withdrawal period?
ketoprofen
Trade names for Macrolides?
Draxxin, Tylan (tylosin),