Emergency Flashcards
What is the AVPU score?
A - alert
V - voice
P - pain
U - unresponsive
What is warm shock?
Hyperdynamic shock
High cardiac output, low peripheral resistance
What is cold shock?
Hypodynamic shock
High systemic vascular resistance and low cardiac output
Why do patients have a narrow pulse pressure in cold shock?
Systolic: low due to low CO
Diastolic: high due to catecholamines that increase systemic vascular resistance to increase venous return
Why do patients with warm shock have a wide pulse pressure?
Lowered diastolic BP
Cytokines increase vascular permeability and cause systemic vasodilation, lowering the systemic vascular resistance
Which vasopressor is used for cold shock?
Adrenaline
Strong B1 activity - increases CO
Given if fluid resuscitation is inadequate
Which vasopressor is used for warm shock?
Noradrenaline
Acts on alpha 1 and beta 1 receptors, producing potent vasoconstriction and a modest increase in cardiac output
Given if fluid resuscitation is inadequate
Is cold or warm shock more common in infants/neonates?
Cold shock
What is the difference between SJS and TEN?
Extent of spread
<10% SJS
>30% TEN
What is the most common cause of SJS?
Drugs (80%)
Antibiotics (sulfonamides), corticosteroids, antiepileptics, alllopurinol, antiretrovirals
What is the pathophysiology of SJS?
Delayed type IV hypersensitivity
Cytotoxic t cells → keratinocyte damage
How does mucous membrane involvement differentiated SJS from staphylococcal scalded skin syndrome?
Involved in SJS
How is SJS treated?
Cease offending drug
Supportive
How is Kawasaki disease diagnosed?
Fever + 4 of
- Fever lasting > 4 days
- Bilateral conjunctival injection (non-exudative)
- Erythematous rash
- Dry/red fissured lips or strawberry tongue
- Oedema of hands/feet
- At least once cervical lymph node > 1.5cm
How are the points in the GCS distributed?
Eye - 4
Verbal - 5
Motor - 6
How are eye responses scored for the GCS?
4 - spontaneous
3 - verbal command
2 - pain
1 - no eye opening
How are verbal responses scored for the GCS?
5 - orientated
4 - confused
3 - inappropriate words
2- incomprehesible sounds
1 - no verbal response
How is motor response scored for the GCS?
6 - obeys commands
5 - localises pain
4 - withdraws from pain
3 - flexion to pain
2 - extension to pain
1 - no motor response
How is DIC from meningococcal treated?
Antithrombin
(thrombotic/organ failure type)
Antithrombin inhibits thrombin and other coagulation factors
What is the empirical treatment for suspected meningococcal sepsis?
Benzylpenicillin IV or IM
How is adrenaline dosed in childhood?
10 micrograms/kg
0.01mL/kg of 1:1000
What doses are children defibrillated with?
4 J/kg
What is the definition of hypoglycaemia in a child?
BGL < 2.6 mmol/L
What fluid type is given for resuscitation/bolus?
0.9% NaCl
How is a child’s fluid bolus calculated?
20mL/kg
0.9% NaCl
How are a child’s replacement fluids calculated?
Weight x % deficit x 10mL
(only replace to 5% in the first 24 hours)