Embryology of the Respiratory Tract Flashcards
What are the lungs derived from?
- Primitive gut tube
What is the term used for the developing lungs?
Respiratory diverticulum
What is the direction of growth for the respiratory diverticulum?
Ventral
- Forward form both
What part of the gut tube is the oesophagus derived from?
- Mid-gut
How do the trachea and oesophagus separate?
- Tracheo-oesophageal septuplets which then forms them as two separate entities
Which week do the two lung buds begin to bifurcate?
- Week 6
- Origins of left and right lung
Name the opening of the respiratory diverticulum
Laryngeal orifice
- Changes from hole to T shape
- Above epiglottis and below trachea
What does the thyroid gland develop from?
Forman cecum
Describe the branching of the bronchi
- Dichotomous branching
- 2 sets on left lung and 3 sets on right
- Primary to secondary
What does dichotomous branching of bronchi mean for the size of lung?
- Lateral enlargement of the lung
- Pushes into the coelomic cavity
Describe the two layers of the coelomic cavity
- Visceral (inside)
- Parietal pleura (outside)
What is the name of epithelium derived from the foregut?
- Endoderm
What is the mesoderm?
(splanchnic)
- Muscles, cartilage, connective tissue
At what week does definite trachealis muscle develop?
- Week 13
What is the trachea-oesophageal fistula?
- False passage between two spaces