Embryology Flashcards
When does implantation of blastocyst occur?
Days 5-6
What two cell types does the trophoblast layer of blastocysts differentiate into?
Syncytiotrophoblasts and Cytotrophoblasts
Describe 3 functions of syncytiotrophoblasts
- Invade uterine wall
- Invade maternal blood vessels in the endometrium by forming lacunae
- Produce hCG
What are cytotrophoblasts?
The cellular layer
Which cells form the embryo?
Epiblast cells from the inner cell mass
What are hypoblast cells
Extraembryonic cells that form tissues that are important for development of the embryo but don’t contribute to it itself
Give 2 functions of the desidual reaction?
- The endometrium becomes Decidua for nutritional a
support and restricts invasion - Prevents the maternal immune response against the fetus
After how many days has implantation occurred (with embryo completely below the lining)
11-12 days
What do the epiblast and hypoblast form?
The bilaminar disc
Which layer of cells form the amniotic sac?
Amniotic ectoderm
Which cell layer forms the fetus?
Epiblast
What structure forms the umbilical cord and when does it start to develop?
The connecting stalk (day 13-14 so post-implantation)
Why does a secondary yolk sac form associated with the hypoblast?
Because the first, primitive yolk sac has regressed.
What is the single layer of extra embryonic ectoderm lined with extra embryonic mesoderm called?
Amnion (amniotic ectoderm)
What is the placenta in early development called
The chorion
Which cells make up the chorion?
Trophoblasts and extra embryonic mesoderm
Which 2 tests screen for Down’s syndrome, Edward’s syndrome or Patau’s syndrome? When can these tests be carried out?
Chorionic villus sampling (11-14 weeks of pregnancy) and Amniocentesis (15-20 weeks of pregnancy)
List the 6 derivatives of trophoblast, amnion and bilaminar disc at 5 weeks
Embryo - derived from epiblast
Amnion - derived from amniotic ectoderm
Amniotic sac is between amnion and embryo
Chorionic plate (extraembryonic mesoderm contribute to chorionic plate)
Chorionic cavity (between extra-embryonic mesoderm and fetus)
Syncytiotrophoblasts (cytotrophoblasts) contribute to chorionic villi