EMBRYOLOGY Flashcards

1
Q

ROSTRAL

A

head end

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2
Q

CAUDAL

A

tail end

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3
Q

NEURULATION

A
  • folding process
  • flat disc folds at edges
  • forms a hollow cylinder
  • 3 germ layers: ectoderm, mesoderm + endoderm
  • neural plate to neural tube
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4
Q

NOTOCHORD

A
  • induce neural plate formation
  • induce ectoblast cells above it to transform into neuroectoblast cells
  • beneath ectoderm, neural groove
  • becomes vertebral column
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5
Q

NEURAL PLATE

A

includes neural crest cells + neural tube

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6
Q

NEURAL TUBE

A
  • precursor to central nervous system (from ectoderm)
  • aka will form brain, spinal cord + retina
  • cylinder of ectodermal cells
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7
Q

NEURAL CREST CELLS

A
  • when neural tube closes + separates from surface they migrate away
  • form structures peripheral to CNS + sensory nerves
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8
Q

NEURAL TUBE ORIGIN

A
  • ectodermal origin
  • neural ectoderm
  • surface ectoderm
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9
Q

NEURAL ECTODERM

A

produces all neurons, glial cells + epithelia of brain, spinal cord, retina e.t.c.

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10
Q

SURFACE ECTODERM

A
  • exterior
  • forms exterior layers of skin
  • e.g. corneal epithelium, conjunctiva, eyelid skin, lens + lacrimal drainage system
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11
Q

WHEN DOES NEURAL TUBE CLOSE?

A

complete closure at end of week 4

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12
Q

SOMITES

A

differentiate into dermis, skeletal muscle, cartilage, tendons + vertebrae

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13
Q

NUMBER OF SOMITES PRESENT BY END OF WEEK 5?

A

42-44 pairs of SOMITES

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14
Q

TWO WALLS OF OPTIC CUP GIVE RISE TO WHICH ADULT STRUCTURE?

A

RETINA

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15
Q

PARAXIAL MESODERM DEVELOPS INTO WHICH MUSCLES OF EYE?

A

OCULAR MUSCLES

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16
Q

ANOPTHALAMIA

A

absence of eye as a result of exposure of the mother to toxic chemicals during pregnancy

17
Q

WHAT IS OPTIC STALK RESPONSIBLE FOR?

A

connecting optic cup to forebrain, becomes optic nerve

18
Q

WHAT IS ABNORMALITY THAT IS THE FAILURE OF THE CHOROIDAL FISSURE TO CLOSE?

A

COLOBOMA

19
Q

SURFACE ECTODERM GIVES RISE TO WHICH STRUCTURES?

A

lens, lacrimal gland, corneal + conjunctival epithelium

20
Q

SCLERA + CHOROID DEVELOP FROM?

A

MESODERM

21
Q

SMOOTH MUSCLES OF IRIS DEVELOP FROM?

A

ectoderm at margin of optic cup

22
Q

LENS PLACODES CREATED FROM WHAT WHEN OPTIC VESICLES MAKES CONTACT WITH IT?

A

ECTODERM

23
Q

RETINA + OPTIC NERVE DEVELOP FROM?

A

NEUROECTODERM

24
Q

OPTIC VESICLES DEVELOPS FROM?

A

DIENCHEPHALON

25
Q

CONGENITAL CATARACT

A

cloudiness of lens

26
Q

REMAINING UNSPECIFIED STRUCTURES OF EYES ARE FORMED FROM THE?

A

MESODERM

27
Q

MICRO-OPTHALAMIA

A

too small eyes, caused by toxoplasmosis

28
Q

SMOOTH MUSCLES OF IRIS DEVELOPS FROM THE?

A

ECTODERM

29
Q

OCULAR MUSCLES DEVELOPED FROM THE?

A

PARAXIAL MESODERM

30
Q

TWO WALLS OF OPTIC CUP GIVE RISE TO?

A

PIGMENTED LAYER + SENSORY LAYER

31
Q

WHAT STRUCTURE MAKES CONTACT WITH OVERLYING ECTODERM + INDUCES IT TO THICKEN TO FORM LENS PLACODE?

A

OPTIC VESICLES

32
Q

OPTIC VESICLE INVAGINATES TO FORM A DOUBLE WALLED?

A

OPTIC CUP