Embryology Flashcards

1
Q

What germ layers does renal system come from?

A

Intermediate mesoderm

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2
Q

Pronephros

A

Intermediate mesoderm

Never functions

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3
Q

Mesonephros

A

Intermediate mesoderm
40 pairs, 20 pairs regress
Functions weeks 6-10 then regresses

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4
Q

Mesonephric duct

A

Condensation of mesenchyme

Canalises grows down beside mesonephros

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5
Q

Metanephros

A

Functions weeks 9-11

Permanent kidney

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6
Q

Metanephros made up of:

A
Metanephric blastema (nephron)
Ureteric bud (collecting part)
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7
Q

Ureteric buds sprout from ____________

A

Mesonephric duct

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8
Q

Ureteric buds penetrate

A

Metanephric blastema

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9
Q

If ureteric bud doesn’t contact metanephric blastema:

A

Kidney agenesis

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10
Q

How are calyces formed?

A

2 periods of ureteric bud intussusception

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11
Q

How is nephron formed?

A

Metanephric blastemal cap responds to ureteric bud
Forms nephric vesicle which elongates
Fuses with collecting system at one end and BVs at another end

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12
Q

Ascent of the kidneys

A

Pelvis: hila point anteriorly

Ascend to adult position (L1) by week 9

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13
Q

Horseshoe kidney

A

Trapped below IMA

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14
Q

Cloaca

A

Expansion of hindgut endoderm

Forms rectum and primitive urogenital sinus

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15
Q

Primitive urogenital sinus

A

Forms bladder, Urethra, definitive urogenital sinus

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16
Q

What splits the primitive urogenital sinus from the rectum?

A

Urorectal septum

17
Q

What happens to ureteric bud?

A

Joins bladder to form ureter

18
Q

What happens to mesonephric duct?

A

Regresses in female, forms trigone

Becomes vas deferens and seminal vesicle in male