Embryology 2 (respiratory) Flashcards
Folding of the embryo gives rise to the primitive
gut
The gut tube forms from the
endoderm
The endoderm forms the gut into three sections:
foregut
midgut
hindgut
the trachea and lungs form from the
foregut
ventral wall
When do the trachea and lungs develop?
week 4 of gestation
The trachea lies ….. to the oesophagus
anterior
what develops to separate the trachea (ventrally) and the oesophagus (dorsally)?
oesophagotracheal septum
Fistula
abnormal or surgical made passage between a hollow or tubular organ and the body surface (or between two hollow or tubular organs)
Tracheoesophageal fistula (TOF)
common (see diagram)
Atresia
where a tube is closed (abnormally)
The visceral pleura develops from the
sphlanchnic mesoderm
Parietal pleura develops from the
somatic mesoderm
The gap between parietal and visceral plaurae is called
pleuroperitoneal canals
What forms around the primitive heat separating pleural cavities from pericardial cavity ?
pleuropericardial folds
pseudoglandular stage set up all pulmonary structures except
those needed for gas exchange
canalicular stage
terminal bronchioles give rise to tubes that make up respiratory part of the lung
saccular stage
formation of alveolar space (and eventually the alveoli)
Surfactant is a mixture of
phospholipids and proteins
Surfactant is secreted by
type 2 penumocytes
Surfactant purpose
counteracts surface tension at air-alveolar interface
Respiratory distress system is also known as
hyaline membrane disease
4 components that develop into the diaphragm
septum transverse
septum transversum develops into …….
of the diaphragm
central tendon
pleuroperitoneal membranes develops into …….
of the diaphragm
primitive diaphragm