EM - Hematology Flashcards
presentation of ALL
-fever
-bone pain
-lymphadenopathy
-lymphoblasts
treatment of ALL
-induction chemotherapy
-intrathecal CNS prophylaxis
-post remission chemo
s/s of AML
-bone marrow failure
-HSM
-auer rods
-myeloblasts
treatment of AML
-induction. hemo
-post remission chemo and stem cell transplant
etiology of aplastic anemia
-failure of hematopoietic bone marrow due to suppression of or injury to stem cells
s/s of aplastic anemia
-increased infections
-pallor, fatigue, dyspnea, palpitation
-bruising, easy bleeding
-purpura and petechiae
Treatment of aplastic anemia
-red cell transfusions
-platelet transfusions
-bone marrow growth factors (EPO)
etiology of sickle cell disease
autosomal recessive
s/s of sickle cell crisis
-pain
-fever
-tachycardia
s/s of sickle cell disease
-jaundice, pallor
-pain and swelling of extremities
-vision changes
-hyperdynamic precordium
-HSM
Diagnosis of Sickle Cell Anemia
blood smear, Hb electrophoresis
treatment of sickle cell anemia
-avoid triggers
-folic acid supplementation
-definitive: stem cell transplant
Also, Hydroxyurea (?)
treatment of sickle cell crisis
Hydration
Oxygenation
Pain relief
etiology of polycythemia vera
JAK2 mutation
s/s of polycythemia vera
-fatigue
-HA
-generalized pruritus (I think especially from a hot shower?)
-bleeding
-stroke
-abdominal pain
-engorged conjunctival and retinal vessels
-plethora
-HCT >54% in males and 51% in females
