Elective Pharmacology

Question 1

basic pharm principles

Answer 1

• too much of a good thing (overdose of BP med = hypotension, alcohol and BP meds = hypotension)
• never take away very powerful/suppressive drug too quickly (steroids, long acting b2 agonists, BB, biologics)

Question 2

-zomibs

Answer 2

cell inhibitor/manipulator
cancer; slow proliferation, inc apoptosis

Question 3

“tinib” “anib”

Answer 3

kinase enzyme inhibitors
non small cell lung cancer, melanoma, thyroid cancer

Question 4

“cept”

Answer 4

recept of; mimics IG

Question 5

TNFinhibitors

Answer 5

“cept”/”mab”

Question 6

NSAIDS MOA

Answer 6

COX: PG/thromboxanes

Question 7

“lukast”

Answer 7

leukotriene rec ant
respiratory med, anti rejection

Question 8

interferons

Answer 8

“-on”

proteins in response to viral attacks
alpha - hep b/c, HPV, hairy leukemia, kaposis sarcoma
beta - MS, AI

s/e: flu like sx, hypothyroidism

Question 9

“limus”

Answer 9

suppress cell mediated immunity (t cell)
anti rejection

Question 10

MOA steroids

b

Answer 10

blockage phospholipase a2 > arachadonate

and thus leukotrients (lipox) and PG/thrombozanes (COX)

Question 11

steroids in order of strength

Answer 11

cortisone
hydrocortisone = “1” of ur cortisol
prenisone
prednisolone
methylprenisode
triamcinalone
paramethasone
dexamethasone
betamethasone