Ectoparasiticides

Question 1

What 2 drugs are used PO against adult fleas?

Answer 1

1. Nitenpyram

2. Spinosad

Question 2

What drug is used PO against flea larvae and eggs?

Answer 2

Lufenuron

Question 3

What 3 drugs are used PO against adult fleas AND ticks?

Answer 3

1. Afoxolaner
2. Fluralaner
3. Sarolaner

Question 4

What 2 drugs are used PO to kill fly larvae?

Answer 4

1. Cyromazine

2. Diflubenzuron

Question 5

Are most ectoparasiticides lipid soluble or water soluble?

Answer 5

Lipid soluble

Question 6

In which species should you avoid the use of anti-cholinergics? Why?

Answer 6

Ruminants - they have 50% the cholinergic receptors as other species

Question 7

What are issues with ectoparasiticides seen in the horse?

Answer 7

1. Sensitive skin
2. Hyperemia
3. Urticaria

Question 8

What are issues with ectoparasiticides seen in the cat?

Answer 8

1. Easily excitable

2. Metabolism problem

Question 9

In what type of weather should you avoid the use of ectoparasiticides?

Answer 9

Hot / humid weather

Question 10

Which of the following need to be done above 40 degrees Fahrenheit: sprays, dips, shampoos, pour-ons, spot-ons, dusts?

Answer 10

1. Dips
2. Sprays
3. Shampoos

Question 11

Which of the following can be done below 40 degrees Fahrenheit: sprays, dips, shampoos, pout-ons, spot-ons, dusts?

Answer 11

1. Pour-ons
2. Spot-ons
3. Dusts

Question 12

When is systemic toxicity more likely, with systemic products or topicals?

Answer 12

Systemic products

Question 13

Name 2 anti-cholinesterase agents

Answer 13

1. Organophosphates

2. Carbamates

Question 14

Name 3 insect growth inhibitors

Answer 14

1. Cyromazine
2. Methoprene
3. Pyriproxyfen

Question 15

Name 2 insect development inhibitors

Answer 15

1. Lufenuron

2. Diflubenzuron

Question 16

Name 2 botanicals

Answer 16

1. Pyrethroids

2. Rotenone

Question 17

Name an octopamine receptor agonist

Answer 17

Amitraz

Question 18

Name 4 Cl- channel blockers

Answer 18

1. Fipronil (Frontline)
2. Afoxolaner (Nexgard)
3. Fluralaner (Bravecto)
4. Sarolaner (Simparica)

Question 19

Name 5 nicotinic receptor agonists

Answer 19

1. Spinosad
2. Nitenpyram (Capstar)
3. Spinetoram
4. Imidacloprid (Advantage)
5. Dinotefuran (Vetra 3D)

Question 20

Name a Na+ channel blocker

Answer 20

Indoxacarb

Question 21

Which of the major classes of ectoparasites are acaricides?

Answer 21

1. Macrocyclic lactones
2. Botanicals
3. Anti-cholinesterase agents
4. Octopamine receptor agonist
5. Cl- channel blocker

Question 22

What are the toxic signs produced by organophosphates?

Answer 22

1. SLUDD
2. Cardiac arrhythmias
3. Muscle fasiculations
4. Ataxia
5. Convulsions

Question 23

What is used to treat an organophosphate toxicity?

Answer 23

Atropine sulfate

Question 24

What 3 drug types should not be used with organophosphates?

Answer 24

1. No cholinergic agonists
2. No skeletal muscle relaxants
3. No CNS stimulants

Question 25

Carbamates are compounds that inhibit ____ by forming ____ bonds.

Answer 25

Carbamates are compounds that inhibit AChE by forming NON-COVALENT bonds.

Question 26

How would you treat a Carbamate overdose?

Answer 26

Atropine

Question 27

What is the MOA of insect growth regulators?

Answer 27

Mimic insect juvenile hormone to prevent molting

Question 28

What are 3 insect growth regulators?

Answer 28

1. Cyromazine
2. Methoprene
3. Pyriproxyfen

Question 29

What is the MOA of insect development inhibitors?

Answer 29

Inhibit chitin synthesis in larvae

Question 30

What are 2 insect development inhibitors?

Answer 30

1. Lufenuron

2. Diflubenzuron