Ectoparasiticides Flashcards

1
Q

What 2 drugs are used PO against adult fleas?

A
  1. Nitenpyram

2. Spinosad

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2
Q

What drug is used PO against flea larvae and eggs?

A

Lufenuron

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3
Q

What 3 drugs are used PO against adult fleas AND ticks?

A
  1. Afoxolaner
  2. Fluralaner
  3. Sarolaner
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4
Q

What 2 drugs are used PO to kill fly larvae?

A
  1. Cyromazine

2. Diflubenzuron

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5
Q

Are most ectoparasiticides lipid soluble or water soluble?

A

Lipid soluble

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6
Q

In which species should you avoid the use of anti-cholinergics? Why?

A

Ruminants - they have 50% the cholinergic receptors as other species

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7
Q

What are issues with ectoparasiticides seen in the horse?

A
  1. Sensitive skin
  2. Hyperemia
  3. Urticaria
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8
Q

What are issues with ectoparasiticides seen in the cat?

A
  1. Easily excitable

2. Metabolism problem

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9
Q

In what type of weather should you avoid the use of ectoparasiticides?

A

Hot / humid weather

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10
Q

Which of the following need to be done above 40 degrees Fahrenheit: sprays, dips, shampoos, pour-ons, spot-ons, dusts?

A
  1. Dips
  2. Sprays
  3. Shampoos
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11
Q

Which of the following can be done below 40 degrees Fahrenheit: sprays, dips, shampoos, pout-ons, spot-ons, dusts?

A
  1. Pour-ons
  2. Spot-ons
  3. Dusts
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12
Q

When is systemic toxicity more likely, with systemic products or topicals?

A

Systemic products

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13
Q

Name 2 anti-cholinesterase agents

A
  1. Organophosphates

2. Carbamates

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14
Q

Name 3 insect growth inhibitors

A
  1. Cyromazine
  2. Methoprene
  3. Pyriproxyfen
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15
Q

Name 2 insect development inhibitors

A
  1. Lufenuron

2. Diflubenzuron

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16
Q

Name 2 botanicals

A
  1. Pyrethroids

2. Rotenone

17
Q

Name an octopamine receptor agonist

A

Amitraz

18
Q

Name 4 Cl- channel blockers

A
  1. Fipronil (Frontline)
  2. Afoxolaner (Nexgard)
  3. Fluralaner (Bravecto)
  4. Sarolaner (Simparica)
19
Q

Name 5 nicotinic receptor agonists

A
  1. Spinosad
  2. Nitenpyram (Capstar)
  3. Spinetoram
  4. Imidacloprid (Advantage)
  5. Dinotefuran (Vetra 3D)
20
Q

Name a Na+ channel blocker

A

Indoxacarb

21
Q

Which of the major classes of ectoparasites are acaricides?

A
  1. Macrocyclic lactones
  2. Botanicals
  3. Anti-cholinesterase agents
  4. Octopamine receptor agonist
  5. Cl- channel blocker
22
Q

What are the toxic signs produced by organophosphates?

A
  1. SLUDD
  2. Cardiac arrhythmias
  3. Muscle fasiculations
  4. Ataxia
  5. Convulsions
23
Q

What is used to treat an organophosphate toxicity?

A

Atropine sulfate

24
Q

What 3 drug types should not be used with organophosphates?

A
  1. No cholinergic agonists
  2. No skeletal muscle relaxants
  3. No CNS stimulants
25
Q

Carbamates are compounds that inhibit ____ by forming ____ bonds.

A

Carbamates are compounds that inhibit AChE by forming NON-COVALENT bonds.

26
Q

How would you treat a Carbamate overdose?

A

Atropine

27
Q

What is the MOA of insect growth regulators?

A

Mimic insect juvenile hormone to prevent molting

28
Q

What are 3 insect growth regulators?

A
  1. Cyromazine
  2. Methoprene
  3. Pyriproxyfen
29
Q

What is the MOA of insect development inhibitors?

A

Inhibit chitin synthesis in larvae

30
Q

What are 2 insect development inhibitors?

A
  1. Lufenuron

2. Diflubenzuron