ECG's and blood pressure Flashcards

1
Q

Explain what the components of an ECG rhythm strip are

A

P wave- depolarisation of atrial contractile fibres produces P wave

P-Q interval- atrial systole- total time taken for the impulse to start in the SA node and to travel to the AV node to begin the ventricular depolarisation and contraction

QRS complex- ventricular contraction- blood pressure in ventricles is high, then falls once blood has been ejected

Q-T interval- total time from the start of ventricular systole to when myocardium around ventricles are fully depolarised

T wave- ventricles are repolarised, and T wave represents relaxation of this phase (ventricular diastole)

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2
Q

How does the nervous system control the normal cardiac rhythm?

A

controlled by the pacemaker and the conduction of impulses through the conduction system
-abnormalities of either system can disrupt normal sinus rhythm causing arrhythmias or dysrhythmias

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3
Q

How does the autonomic nervous system support the heart?

A
  1. sympathetic nervous system= raises the heart rate by stimulating the B1 adrenergic receptors
  2. parasympathetic nervous system= via the vagus nerve, lowering the heart rate
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4
Q

what is the SA node?

A

-a cluster of cells that is triggered by the autonomic nervous system, its impulse leads the contracting of the heart
-it is located at the top of the right atrium near the superior vena cava entrance

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5
Q

Explain how the SA node stimulates the heart beat

A

-generates electrical impulse which spreads across the two atria, to the myocardial cells and atrial contraction occurs
-the SAN can independently initiate an electoral impulse to create a heart beat, = pacemaker

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6
Q

How is the AV node involved in contracting the heart beat?

A

-located at the intertribal septum near the tricuspid valve
-the impulse that goes to the atria doesn’t reach the AV node as there is fibrous connective tissue that doesn’t conduct impulses well
-the function of the AV node is to momentarily delay the impulse to the ventricles, ensuring that the ventricles are full of blood before contracting, maintaining peak cardiac output

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7
Q

What is the bundle of His involvement in contracting the heart beat?

A

-from the AV node the impulse travels down the Bundle of His separating into the 2 branches which head down towards respective ventricles
-impulses travel faster down the left bundle branch as left myocardium is thicker, allowing both ventricles to contract at the same time

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8
Q

What is the purkinje fibres involvement in contracting the heart beat?

A

-the bundle branches end in the purkinje fibres which stretch deep into the myocardial tissue, therefore conducting the impulse through the myocardium
-myocytes contract together creating the ventricular contraction

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9
Q

How is the myocardium structured to help with muscle contraction?

A

-muscle contains myofibrils in bundles composed of 2 types of filament: myosin (thick) and actin (thin, composed of troponin and tropomyosin)

-interconnecting cross bridges along the myosin filament help the muscles to contract, whereby myosin flies over actin filaments using ATPase

-each myofibril consists of a chain of sarcomeres which can contract, containing both dark and light bands

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10
Q

What is the actual process of muscle contraction?

A

-initaited by intracellular calcium concentration and release of calcium ions from sarcoplasmic reticulum

-proteins troponin and tropomyosin regulate contraction according to calcium levels

-immediate energy is supplied by hydrolysis of ATP by actin-myosin ATPase
-done on the cross-bridges formed between myosin and actin filaments

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11
Q

What is cardiac output?

A

-The amount of blood pushed out of the left ventricle over a minute
-so this is stroke volume (volume of blood in one beat) multiple by heart rate (beats per minute)

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12
Q

How is the heart beat controlled neuraly?

A

the centre that regulates blood pressure is located in the brain, in the reticular formation of the medulla and in the pons
-the pons contains both the vasomotor and cardiac control centres

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13
Q

How does the cardiovascular centre control the heart beat?

A

-initiates impulses via the parasympathetic nervous system, through the vagus nerve (slows HR) and sympathetic nervous system through the spinal cord and peripheral sympathetic nerves (increases HR and contractibility)
-these control the rate of the heart beat and the force of contraction

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14
Q

Explain how baroreceptors monitor blood pressure

A

-pressure sensitive and located in the blood vessel walls in the carotid and aortic arteries
-respond to changes in blood volume as they are stretched
-baroreceptors respond to change where blood circulating volume is triggered by the pons and medulla to increase heart rate and trigger sympathetic nervous system to constrict the blood vessels

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15
Q

Explain how chemoreceptors monitor chemical blood changes?

A

-monitor blood levels of oxygen, carbon dioxide and hydrogen ions in the carotid and aortic bodies
-their main function is to regulate respiration to maintain the body’s pH level and oxygenation, but these can trigger vasoconstriction increasing the peripheral vascular resistance

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16
Q

How does Anti-diuretic hormone (ADH) regulate blood pressure?

A

-released by posterior pituitary gland when the circulating blood volume falls or when blood pressure falls and works directly on the blood vessels causing vasoconstriction

-overtime managing blood pressure is undertaken by the kidneys and the regulation of extra-cellular fluid volume. when the body has excess ECF, blood pressure will rise, increasing the rate at which the body excretes water in urine

17
Q

How does Renin- angiotensin- aldosterone system (RAAS) regulate blood pressure?

A

-the main system used to regulate blood pressure
-renin is made and stored, then released by juxtameduallary cells in the kidney
-release is triggered by the increase in sympathetic nervous system stimulation or by a decrease in blood pressure

-renin leaves kidney via blood stream and travels to lungs where it works as an enzyme converting a plasma protein angiotensinogen into angiotensinogen 1, then into angiotensinogen 2

18
Q

How does angiotensiongen 2 work in the RAAS to regulate blood pressure?

A

-works directly on the vessels- strong vasoconstrictor and increases the peripheral vascular resistance throughout the body
-in the kidney is reduces how much sodium is excreted by increasing the reabsorption on the proximal convoluted tubule
-in the adrenal gland it triggers the production of aldosterone

-aldosterone supports the long term increase in blood pressure by increasing retention of sodium and water by the nephron, as angiotensiongen 2 only has a half life of a few minutes once developed

19
Q

How does Atrial Natriuretic Peptide (ANP) regulate blood pressure?

A

-affects blood pressure by causing blood pressure to fall at vasodilation and inhibition of renin production
-ANP is produced in the right atrium in response to hypertension