Early Embryology 1 Flashcards
Define pre-embryonic, embryonic and foetal periods of development
Pre-Embryonic: Week 1-2 > cell production
Embryonic: Week 3-8 > building complex systems
Foetal: Week 9-38 > growth
What changes take place as the zygote moves down the Fallopian tube?
- Oocyte fertilised by sperm in Ampulla to form a zygote
- Cells in zygote continue to divide when travelling along the Fallopian tube
Define: Zygote, Cleavage, Zona Pellucida and Morula
Zygote - An oocyte fertilised by a sperm, diploid cell
Cleavage - Furrow that forms during Mitosis division
Zona Pellucida - Glycoprotein shell that protects egg from further sperm invasion
Morula - Ball of totipotent cells
Define Ovary, Fallopian Tube and Uterus
Ovary - Female reproductive organ in which ova are produced
Fallopian Tube - One of a pair of tubes along which ova travel from the ovaries to the uterus
Uterus - Site where a fertilised egg implants and develops into a foetus
How does a blastocyst form?
A fluid filled cavity that opens up in the morula during cell division
What are the initial stages of implantation?
- Morula differentiates into mass of pluripotent cells
- Blastocyst hatches from Zona Pellucida
- Can now interact and implant to the uterine surface
- Embryo and Placenta are formed
Define blastocyst, trophoblast and inner cell mass
Blastocyst - Mass of differentiated cells 5-6 days post fertilisation that helps implantation
Trophoblast - Layer of cells on the outside of the blastocyst supplying structure and nourishment
Inner Cell Mass - Collection of embryoblast cells attached on one wall of the trophoblast layer
Define implantation, cytotrophoblast and syncytiotrophoblast
Implantation - Process of a blastocyst joining to the uterine surface
Cytotrophoblast - Inner layer of the trophoblast
Syncytiotrophoblast - Transport barrier and outer layer of the trophoblast (multi-nucleated sheet)
How does the embryonic disc form from the inner cell mass?
Inner cell mass differentiates into bilaminar disc made of epic lasts and hypoblasts below an amniotic cavity
Define: bilaminar disc and germ layer
Bilaminar Disc - Layer of epiblasts and hypoblasts evolved from the embryoblast
Germ Layer - Group of cells in an embryo that contribute to formation of organs and tissues
Define ectoderm, mesoderm and endoderm
Ectoderm - Outermost layer of cells or tissues of an embryo in early development
Mesoderm - Middle layer of cells or tissues of an embryo
Endoderm - Innermost layer of cells or tissues of an embryo
Define Primitive Streak and Gastrulation
Primitive Streak - Transient structure whose formation marks the start of gastrulation
Gastrulation - Process by which the inner cell mass is converted into the trilaminar disc
What is a trilaminar embryonic disc?
When an embryo exists as3 different germ layers - ectoderm, mesoderm and endoderm
What are the derivatives of the ectoderm layer?
- Nervous system
- Epidermis
What are the derivatives of the mesodermal layer?
- Heart
- Kidneys
- Bones
- Muscle
- Connective tissue