E3 cerebellum Flashcards

1
Q

primary fissure

A

separates anterior and posterior lobes

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2
Q

posterolateral fissure

A

separates posterior and floculonodular lobes

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3
Q

floculonosudlar lobe

A

balance and eye movements

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4
Q

3 layers

A

molecular
purkinje
granule

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5
Q

3 nuclei

A

fastigial
interposed
dentate

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6
Q

inhibitory cells

A

basket, golgi, stellate purkinje

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7
Q

excitatory cell

A

granule

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8
Q

molecular layer

A

basket and stellate cells
dendirtes of purkinje
climbing fibers

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9
Q

purkinje layer

A

cell bodies of only output

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10
Q

granule

A

golgi and granule cells

mossy fibers

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11
Q

climbing fibers

A
from inferior olive via ICP
excite deep nuclei and purkinje cells
1 collateral per purkinje
1-10 collaterals
function=motor adaptaion and motor learnign
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12
Q

mossy fibers

A

inform cerebellum about planned and ongoing movements
from spinal cord and brainstem
to deep nuclei and granule cells

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13
Q

parallel fibers

A

from granule cells (activated by mossy fibers)
to purkinje dendrites
excitatory

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14
Q

simple cerebellum circuit

A

intended and ongoing info in via mossy and climbing fibers to cerebellar cortex and deep neurons
differences between planned and actual analyzed and adjuted and sent out thorugh purkinje fibers

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15
Q

somatotopy of cerebellum

A
head neck trunk in vermis
sent down to fastigial nuclei
arms and legs laterally in paravermis and lateral hemispheres
to interposed and dentate
dual reps in anteror and posterior lobes
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16
Q

medial zone

A

flocculonodular lobe and vermis
regulate fastigial and lateral vestibular nuclei
for balance, eye movement, postures, locomotion and trunk

17
Q

lateral zone

A

paravermis and cerebral hemispheres
regulate interposed and dentate nuclie
distal muscles and motor planning

18
Q

5 inputs to medial zone

A
corticopontien
spinall/trigeminal
vestibular
reticular
inferior olive
all go to vermis and flocculonodular lobe
19
Q

corticopontine input

A
to medial zone -  lower body
to lateral zone - upper body
motor command from cortex
to pontine nuclei 
crosses at decussation of transverse pontine fibers
enter through MCP
20
Q

spinal and trigeminal input

A

to medial zone and lateral zone
DSCT - lower body proprioception
cuneocerebllar tract - upper body proprioception
trigeminocerebellar tract - info from face
all come in through ICP ipsilaterally

21
Q

VSCT

A

efferent copies from spinal cord
cross at ventral white commissure
cross again at SCP
to Medial zone and lateral zone

22
Q

vestibular cerebellar tract

A

balance
ipsilateral ICP
to medial zone

23
Q

reticulocerebellar tract

A

cutaneous
ispsi ICP
to medial zone and lateral zone

24
Q

olivocerebellar tract

A

timing and motor learnig
from inferior olive
cross before ICP so contra
to medial zone and lateral zone

25
Q

medial and lateral zone outputs

A

shoudl just draw it

26
Q

medial zone and ICP lesions

A
bilatearl deficits
truncal ataxia
wide drunk gait
vertigo and nystagmus
ICP=hypertonicity
dysarthria (slurred speech)
27
Q

lesion of lateral sone and SCP

A
hypotonia
initiation delays
difficulty wiht multijoint movements
dysmetria
intention tremor
dysdiadochokinesia