E&T: Digestion and Absorption Flashcards

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1
Q

What are carbohydrates broken down by?

A

Amylase

Membrane-bound disaccharidases

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2
Q

Amylase

A

Digestive enzyme that catalyses the conversion of starch into maltose, which involves the hydrolysis of glycosidic bonds in starch.

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3
Q

Where is amylase produced?

A

By salivary glands and pancrease

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4
Q

Membrane-bound disaccharidases

A

Enzymes attached to cell membranes of epithelial cells lining the ileum which break down disaccharides into monosaccharides.

Hydrolyses glycosidic bonds.

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5
Q

What is the disaccharidase for:

  • maltose?
  • sucrose?
  • lactose?
A
  • maltase
  • sucrase
  • lactase
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6
Q

How can monosaccharides be transported across the cell membranes of the ileum epithelial cells?

A

Via specific transporter proteins

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7
Q

What are lipids broken down by?

A

Lipase

Bile salts

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8
Q

Lipase

A

Enzymes that catalyse the breakdown of lipids into monoglycerides and fatty acids.

Hydrolyses ester bonds.

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9
Q

Where are lipases made?

Where do they work?

A

In pancreas

Work in small intestine

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10
Q

Where are bile salts produced?

A

Liver

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11
Q

Bile salts

A

Emulsify lipids - cause them to form small droplets which increases the SA available for lipases to work on

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12
Q

What are proteins broken down by?

A

Exopeptidases and endopeptidases

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13
Q

Once the lipid has been broken down (bile salts), what happens?

A

Monoglycerides and fatty acids stick to the bile salt to form micelles

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14
Q

Endopeptidases

A

Hydrolyse peptide bonds within a protein.

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15
Q

Give an example of an endopeptidase:

A

Pepsin - released into stomach by cells in stomach lining.

Only works in acidic conditions eg hydrochloric acid in stomach

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16
Q

Exopeptidases

A

Hydrolyse bonds at the ends of protein molecules - remove single amino acids from proteins.

17
Q

Dipeptidases

A

Exopeptidases that work specifically on dipeptides - act to separate the two amino acids by hydrolysising peptide bonds between them.

18
Q

Where are dipeptidases often located?

A

Cell-surface membrane of epithelial cells in small intestine

19
Q

Where are the products of digestion absorbed across?

A

Ileum epithelium into the bloodstream

20
Q

How are these monosaccharides absorbed:

  1. Glucose
  2. Galactose
  3. Fructose
A
  1. Absorbed by active transport with sodium ions via a co-transporter protein.
  2. Absorbed the same way as glucose.
  3. Absorbed via facilitated diffusion through a different transporter protein.
21
Q

How are glcyerides and fatty acids absorbed?

A
  • Micelles move them towards epithelium.
  • As micelles constantly break, they release monoglycerides and fatty acids to be absorbed.
  • Lipid-soluble so diffuse directly across epithelial cell membrane.
22
Q

How are amino acids absorbed?

A
  • Via co-transport.
  • Sodium ions actively transported out of ileum epithelial cells into blood.
  • Creates sodium ion concentration gradient.
  • Sodium ions diffuse from lumen of ileum into epithelial cells via sodium-dependent transporter proteins - carry amino acids with them.
23
Q

Digestive enzyme that catalyses the conversion of starch into maltose, which involves the hydrolysis of glycosidic bonds in starch.

A

Amylase

24
Q

Enzymes attached to cell membranes of epithelial cells lining the ileum which break down disaccharides into monosaccharides.

Hydrolyses glycosidic bonds.

A

Membrane-bound disaccharidases

25
Q

Enzymes that catalyse the breakdown of lipids into monoglycerides and fatty acids.

Hydrolyses ester bonds.

A

Lipase

26
Q

Emulsify lipids - cause them to form small droplets which increases the SA available for lipases to work on

A

Bile salts

27
Q

Hydrolyse peptide bonds within a protein.

A

Endopeptidases

28
Q

Hydrolyse bonds at the ends of protein molecules - remove single amino acids from proteins.

A

Exopeptidases

29
Q

Exopeptidases that work specifically on dipeptides - act to separate the two amino acids by hydrolysising peptide bonds between them.

A

Dipeptidases