CELLS: Diffusion Flashcards

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1
Q

What is diffusion?

A

The net movement of molecules or ions from a region where they are more highly concentrated to a region where their concentration is lower until they are evenly distributed.

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2
Q

In diffusion, can particles diffuse both ways?

A

Yes, but the net movement will be to the area of lower concentration.

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3
Q

What is the concentration gradient?

A

The path from an area of higher concentration to an area of lower concentration.

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4
Q

In diffusion, how do particles diffuse across the concentration gradient?

A

They diffuse down the concentration gradient.

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5
Q

Can particles diffuse across cell membranes?

Give an example.

A

Yes, as long as they can move freely through the membrane.

  • Eg. oxygen and carbon dioxide can diffuse easily through cell membranes because they’re small, so they can pass through spaces between the phospholipids.*
  • Also, they are non-polar so are soluble in lipids, so can dissolve in hydrophobic bilayer.*
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6
Q

When molecules diffuse directly through a cell membrane.

A

Simple diffusion.

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7
Q

Simple diffusion.

A

When molecules diffuse directly through a cell membrane.

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8
Q

Why is diffusion considered passive?

A

It does not rely on energy from an external source, for example ATP.

Instead energy comes from the natural, inbuilt motion of the particles.

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9
Q

What molecules might find it harder to diffuse through the phospholipid bilayer?

A

Charged particles and larger molecules.

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10
Q

Why might some molecules find it harder to diffuse through the phospholipid bilayer?

How might these molecules diffuse instead?

A

Larger molcules = due to size would diffuse extremely slowly.

Charged particles = would diffuse slowly, as thye are water soluble and the centre of the bilayer is hydrophobic.

They might diffuse through carrier protiens or channel proteins in a process known as facilitated diffusion.

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11
Q

What are the similarities and differences between simple diffusion and facilitated diffusion?

A

Similarities:

  • Passive process - does not rely on external source like ATP.
  • Moves particles down concentration gradient.

Differences:

  • Facilitated diffusion uses carrier proteins and channel proteins.
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12
Q

What is the role of carrier proteins in facilitated diffusion?

A

To move large molecules across membranes.

Different carrier proteins faciliatate diffusion of different molecules.

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13
Q

What are the two proteins involved in facilitated diffusion?

A

Carrier proteins and channel proteins.

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14
Q

Explain the mechanisms involved in large molecules diffusing across the cell membrane:

A
  • Large molecule attaches to carrier protein in membrane.
  • Protein changes shape.
  • This releases molecule on the opposite side of the membrane.
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15
Q

Explain the mechanisms involved with diffusing charged particles across the cell membrane:

A
  • Channel proteins form pores in cell membrane.
  • Charged particle diffuses though this.
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16
Q

What is the role of channel proteins in facilitated diffusion?

A

Assist in the diffusion of charged particles.

17
Q

In simple diffusion, what does the rate depend on?

A
  • Concentration gradient = higher it is, faster the rate (therefore, as diffusion takes place, the rate decreases as difference in concentration decreases).
  • Thickness of exchange surface = thinner, the faster the rate as particles have a shorter distance to travel through.
  • Surface area = larger, the faster the rate, as more particles can be exchanged in the same amount of time.
18
Q

Give an example of how increased surface area increases diffusion rate:

A

Microvilli on epithelial cells in small intestine

  • Projections formed by the cell-surface membrane folding up on itself.
  • Give the cell a larger surface area.
  • Larger surface area means more particles can be exchanged in the same amount of time.
19
Q

What factors affect the rate of facilitated diffusion?

A
  • Concentration gradient = higher it is, faster the rate (therefore, as diffusion takes place, the rate decreases as difference in concentration decreases).
  • Number of channel or carrier proteins = once all proteins in membrane are in use, facilitated diffusion can’t happen any faster. So greater the number of channel/carrier proteins, the faster the rate.
20
Q

Give an example of how having more channel proteins increases the rate of facilitated diffusion:

A
  • Kidney cells are adapted to have lots of aquaporins.
  • These allow the cells to reabsorb a lot of water that would have otherwise been excreted from the body.
21
Q

What are aquaporins?

A

Special channel proteins that allow the facilitated diffusion of water through cell membranes.