E. coli Flashcards
At what concentration is e. coli found in the large intestine
millions of cells/g
How is e. coli categorized into different pathotypes
Based on their ability to produce toxins, adhere to epithelial cells, and ability to invade epithelial cells
How how e. coli acquired most of its pathogenic traits
Through HGT
How is e. coli categorized into different serotypes
Based on O, H and K antigens
In e. coli, the O antigens determines the __ and the H antigen identifies the __
Serogroup, serotype
Unmarked e. coli strains are…
Commensal, extraintestinal pathogenic, or avian pathogenic
What things are constantly moving in and out of e. coli genomes
Prophages, genomic islands, and plasmids (shigella toxin is determined by the presence of these)
Most virulence factors are derived from…
Mobile genetic elements
How is STEC defined
By the presence of Shiga toxin 1 or 2 acquired from bacteriophage infection
What is HUS
Caused by the destruction of RBCs which clog the filtering system in the kidneys, leading to kidney failure
What is LEE negative STEC called
EHEC (enterohemorrhagic e. coli)
What is the most common serotype of STEC
O157:H7
What is the most common bacterial pathogen identified in patients with diarrhea
Enteroaggregative e. coli (travelers diarrhea)
What are two pathogens associated with traveler’s diarrhea
ETEC and EAEC
What is the only e. coli to have a heat stable toxin
ETEC
