Campylobacter Flashcards
Two kill campylobacter, what temp do you have to cook to
An internal temp of 70C for two minutes
What are three ways campylobacter can be transmitted
Through consumption of undercooked or contaminated food OR Via contact with animals OR Person-person (fecal-oral route)
What time of year do campylobacter infections peak
In the summer
What are some reasons behind the peak season of campylobacter
Ambient temp, human behaviour, seasonal variation in chicken flocks, flies are more active (can carry it)
What is the most common type of campylobacter, and what are its reservoirs and symptoms of disease
C. jejuni
Poultry, pigs, dogs, cats, birds, insects
Gastroenteritis, septicemia, meningitis, abortion
How many gastroenteritis cases are caused by C. jejuni
90% (rest C. coli)
What is the most extensively studied extraintestinal manifestation associated with campylobacter infection
GBS and Miller Fisher syndrome
What is the main difference between MFS and GBS
The first nerve groups to be affected in MFS are in the head, thus affecting eye muscles and balance (paralysis in GBS starts in legs
What are some clinical manifestations of different campylobacter infections
Gastro, brain abscess, periodontitis, GBS/MFS, IBD, esophageal disease, bacteremia/septicemia
What are some factors involved in the molecular pathogenesis of campylobacter
Motility, adhesion, protein secretion/invasion, toxin production, actin polymerization and endocytosis