DTaP, Tdap, and TD

Question 1

Diptheria and types of vaccines

Answer 1

Sx is caused by a toxin

DTaP and DT - children under 7

Tdap and Td - older children through adults

Question 2

Tetanus

Answer 2

Lockjaw
Caused by toxin

Tx is tetanus immune globulin or IVIG

Question 3

Pertussis

Answer 3

Whooping cough

Pertussis toxin vaccine…also specific for other parts

Question 4

How does toxin vaccine work?

Answer 4

Normally, toxin binds celullar receptors, tkaen in and then toxin redistributed…HERE, the AB binds the toxin so it cannot bind to and enter cells

Question 5

IgA function

Answer 5

Dimeric IgA transported into gut lumen through epithelila cells…it binds to layer of mucus in the gut and can then nuetralize pathogens

Question 6

Vaccine scheulde

Answer 6

DTap - infants (2 mos to 4-6 years…5 doses)

Booster with Tdap at 11 years

TD every 10 years after than

Preg - Tdap between 27-33 weeks

Question 7

Maternal antibodies

Answer 7

IgG crosses placenta

Dimeric IgA through breat milk