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Year 2 ALS > Drugs list Block 13 > Flashcards

Drugs list Block 13 Flashcards

1
Q

Isoniazid

A

Prodrug- inhibits synthesis if mycelic acids in mycobacterium TB cell wall
Bacteriacidal
Treats TB

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2
Q

Ethambutol

A

Inhibits arabinosyl transferases involved in cell wall synthesis to increase cell wall permeability
Bacteriacidal
Treats TB

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3
Q

Pyrazinamide

A

Active only at slightly acidic pH
Disrupts membrane potential and interferes with fatty acid synthesis
BActeriacidal
Treats TB

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4
Q

Salbutamol

A

Beta 2 agonist
Short acting, causes bronchodilator
Asthma

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5
Q

Salmetrol

A

Beta 2 agonist
Long acting
Asthma

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6
Q

Formetrol

A

Long acting beta 2 agonist
Quicker acting and more potent than salmetrol
Asthma

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7
Q

Budesonide

A 
Inhibits mast cells, eosinophils, neutrophils, macrophages and lymphocytes
Anti-inflammatory
Corticosteroid
Asthma
Crohn
UC
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8
Q

Montelukast

A

Leukotriene receptor antagonist

Used for asthma if beta agonists and steroids not effective

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9
Q

Ipratropium

A

Anticholinergic agent
Inhibits muscarinic cholinergic receptors, resulting in decrease in cGMP concentration and causing smooth muscle relaxation
COPD

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10
Q

Verapamil

A

Blocks L type calcium channels in heart to reduce heart rate and blood pressure
Class IV antiarrythmic

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11
Q

Diltiazem

A

Blocks calcium channels so less intracellular calcium- causes coronary artery dilation, increases oxygen to myocardium, decreases blood pressure and reduces after load
Calcium channel inhibitor
Hypertension
Angina

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12
Q

Atropine

A

Inhibits muscarinic M2 receptor

Treats bradycardia

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13
Q

Glyceryl trinitrate

A

Nitroglycerin converted to NO- activates gluanylate cyclase- stimulates CGMP- activates protein kinase G- vasodilation
Angina treatment

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14
Q

Amiodarone

A

Class III antiarrythmic
Prolongs myocardial action potential by blocking K channels
Treats AF and VF

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15
Q

Adenosine

A

Inhibits slow inward calcium channels and activation of adenylate cyclase, causes relaxation of smooth muscles. Needed to slow conduction through AV node
Antagonised by methylxantines like caffeine
Treats SVT

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16
Q

Lidocaine

A

Class 1b antiarrthymic that blocks Na channels during phase 0 of cardiac action potential
SVT

17
Q

Chlorpromazine

A

Antagonist on dopaminergic receptors

Sedative, antiemetic, psychotropic agent

Year 2 ALS (14 decks)

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