Drug Toxicity Flashcards
Lithium Therapeutic and Toxic level?
Therapeutic = 0.6 - 1.2
Toxic level = greater than or equal to 2
Linoxin / Digoxin Therapeutic and Toxic level?
Therapeutic = 1-2
Toxic = greater than or equal to 2
If given the answer 2 pick it for toxic - it can go either way.
Aminophylline - bronchodialtor therapeutic and Toxic level?
Therapeutic = 10-20
Toxic level = > 20
Dilantin therapeutic and Toxic level?
Toxic level = > 20
Bilirubin - newborn therapeutic and Toxic level?
Therapeutic = 8
Elevated = 10-20
Toxic level = > 20
What is a common sign of Pathologic Jaundice
Arching Neck extension
Any hint of extension is ominous in jaundice child
Define Kernicterus
Kernicterus is a very rare type of brain damage that occurs in a newborn with severe jaundice. It happens when a substance in the blood, called bilirubin, builds up to very high levels and spreads into the brain tissues. This causes permanent brain damage. Bilirubin in cerebral spinal fluid = meningitis or encephilities.
Define Opisthotonos
Spasm of the muscles causing backward arching of the head, neck, and spine, as in severe tetanus, some kinds of meningitis, and strychnine poisoning.