Drug/nutrient interactions

Question 1

Drug/nutrient interaction defined.

Answer 1

Alterations in nutritional status that can affect a drug’s metabolism and/or some drugs can affect nutritional status.

Question 2

Synergistic

Answer 2

THe combined effect is greater than the sum of the individual effects.

Question 3

Antagonistic

Answer 3

interaction of two or more substances such that the actin of any one of them on living cells or tissues is lessened.

Question 4

Factors that affect the risk of such synergistic and/or antagonistic interactions include:

Answer 4

1. age or gender
2. the disease condition or conditions under treatment can affect nutrient absorption and utlization
3. timing of meals on drug administration
4. duration of administration
5. drug form (pill, liquid) and route (orally, enteral, IV)
6. dosage and frequency of administration
7. number of drugs being administered concurrently
8. diet quality
9. nutritional status and/or body composition
10. use of dietary/herbal supplements