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PCOL MIDTERMS > DOA (feel ko lang lalabas hahaha) > Flashcards

DOA (feel ko lang lalabas hahaha) Flashcards

1
Q

Antidote used for benzodiazepine toxicity

A

Flumazenil

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2
Q

Benzodiazepines bind to what GABA receptor?

A

GABA A

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3
Q

This pyrazolopyrimidine is used for sleep disorder

A

Zaleplon

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4
Q

Nonselective opioid antagonist and partial agonist used for treating addiction

A

Naltrexone

naloxone is for opioid overdose

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5
Q

A serotonin receptor partial agonist

A

LSD

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6
Q

A CB1R agonist

A

cannabinoids

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7
Q

Drug used for treatment of alcoholism and opioid addiction

A

Naltrexone

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8
Q

ANTAGONIST/MIXED/STRONG/MODERATE/WEAK AGONIST?

Methadone

A

Strong

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9
Q

ANTAGONIST/MIXED/STRONG/MODERATE/WEAK AGONIST?

Oxycodone

A

Moderate

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10
Q

ANTAGONIST/MIXED/STRONG/MODERATE/WEAK AGONIST?

Nalbuphine

A

Mixed

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11
Q

ANTAGONIST/MIXED/STRONG/MODERATE/WEAK AGONIST?

Kratom

A

Mixed

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12
Q

ANTAGONIST/MIXED/STRONG/MODERATE/WEAK AGONIST?

Naloxone

A

Antagonist

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13
Q

ANTAGONIST/MIXED/STRONG/MODERATE/WEAK AGONIST?

Tramadol

A

Moderate

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14
Q

Affinity to MU/KAPPA/DELTA:

endorphins > enkephalins

A

Mu receptors

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15
Q

Affinity to MU/KAPPA/DELTA:

endorphins < enkephalins

A

Delta receptors

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16
Q

DELTA/MU/KAPPA:

endorphins = enkephalins

A

Kappa receptors

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17
Q

G-PROTEIN/IONOTROPIC/BIOGENIC AMINES?

Alcohol

A

Ionotropic

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18
Q

G-PROTEIN/IONOTROPIC/BIOGENIC AMINES?

Amphetamine

A

Biogenic Amines

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19
Q

G-PROTEIN/IONOTROPIC/BIOGENIC AMINES?

Cannabinoids

A

G-protein

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20
Q

G-PROTEIN/IONOTROPIC/BIOGENIC AMINES?

Ketamine

A

Ionotropic

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21
Q

G-PROTEIN/IONOTROPIC/BIOGENIC AMINES?

Mescaline

A

G-protein

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22
Q

G-PROTEIN/IONOTROPIC/BIOGENIC AMINES?

Psilocybin

23
Q

G-PROTEIN/IONOTROPIC/BIOGENIC AMINES?

Ecstasy

A

Biogenic Amines

24
Q

G-PROTEIN/IONOTROPIC/BIOGENIC AMINES?

Phencyclidine

A

Ionotropic

25
Q

Acetylcholine receptor agonist

(nAChR agonist)

26
Q

NMDA receptor antagonist

A
  • phencyclidine
  • ketamine
27
Q

Dopamine transporter blocker

28
Q

reverses serotonin transport

29
Q

GABAa receptor (positive) modulator

A

Benzodiazepine

30
Q

Blocks orexins that promote sleep onset & duration

A

Suvorexant

31
Q

Partial serotonin agonist is used for generalized anxiety states

32
Q

Activates the melatonin receptors in suprachiasmatic nuclei

33
Q

Barbiturates/Benzodiazepines/Both/Neither

Has high affinity to GABA-B receptors

A

Neither

GABA-A only

34
Q

Barbiturates/Benzodiazepines/Both/Neither

Crosses the placental barrier

A

Both

all sedative-hypnotics cross the placental barrier

35
Q

Partial agonist of nicotinic acetylcholine receptor used in smoking cessation

A

Varenicline

36
Q

Enumerate:

Endogenous cannabinoids

A
  • 2-arachidonyl glycerol
  • anandamine
37
Q

Enumerate:

Exogenous cannabinoids

A
  • THC
  • marijuana
  • nabilone
  • dronabinol
  • nabiximol
38
Q

Barbiturates/Benzodiazepines/Both/Neither

Steeper dose-response curve

A

Barbiturates

39
Q

ANTAGONIST/MIXED/STRONG/MODERATE/WEAK AGONIST?

Propoxyphene

40
Q

Barbiturates/Benzodiazepines/Both/Neither

Binds to GABA-A receptors

41
Q

MU/KAPPA/DELTA/ALL:

Analgesic mechanism

42
Q

MU/KAPPA/DELTA/ALL:

Respiratory depressant action

A

Mu receptor

43
Q

MU/KAPPA/DELTA/ALL:

Sedative actions

A

Mu receptor

44
Q

MU/KAPPA/DELTA/ALL:

Psychotomimetic effects

A

Kappa receptor

45
Q

A benzodiazepine for** delirium tremens**

46
Q

NMDA ANTAGONIST

for treatment of alcoholism

A

Acamprosate

47
Q

THIOPENTAL/SECOBARBITAL/PHENOBARBITAL

For anesthesia

A

Thiopental

48
Q

THIOPENTAL/SECOBARBITAL/PHENOBARBITAL

Insomnia

A

Secobarbital

49
Q

THIOPENTAL/SECOBARBITAL/PHENOBARBITAL

Seizure disorders

requires a loading dose

A

Phenobarbital

50
Q

Partial agonist at 5-HT

51
Q

Excessive or unreasonable anxiety about life circumstances

A

generalized anxiety disorder

52
Q

What type of sedation is more common with benzodiazepines that have slow elimination rates?

A

daytime sedation

53
Q

Newer hypnotics that act like benzodiazepines (3)

A
  • eszopiclone
  • zaleplon
  • zolpidem

PCOL MIDTERMS (10 decks)

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