DNA Replication And Recombination

Question 0

Term for DNA + Histones

Answer 0

Nucleosome

Question 1

Tagging of chromatin so that nuclear DNA is replicated once and only once

Answer 1

Replication Licensing

Question 2

Histone molecule which attaches to linker DNA

Answer 2

H1

Question 3

Examples of constitutive heterochromatin

Answer 3

Telomeres and Centromeres

Question 4

Actively-replicating chromatin

Answer 4

Euchromatin

Question 5

Separates core histones, resulting in a “beads on a string” appearance

Answer 5

Linker DNA

Question 6

Modifications that decrease the affinity of histones and DNA

Answer 6

Acetylation and phosphorylation by histone acetyltransferase and histone deacetylase

Question 7

TRUE/FALSE: introns are DNA coding regions

Answer 7

FALSE

Question 8

Dinucleotide repeates of AG on one strand and TG on the other

Answer 8

Microsatellite Sequences

Question 9

Counterpart of replication protein A (RPA) in prokaryotes

Answer 9

Single stranded DNA-binding protein (SSB)

Question 10

Short sequence composed almost completely of AT base pairs

Answer 10

Origin of replication (ORI)

Question 11

Function of SSB

Answer 11

Prevents re-annealing of parental DNA strands

Question 12

Remove supercoils that interfere with further unwinding of DNA

Answer 12

Topoisomerases

Question 13

TRUE/FALSE: gyrase cleaves one strand of the supercoil; target of fluoroquinolones

Answer 13

FALSE: swivelase cleaves one strand and gyrase cleaves two

Question 14

RNA scaffold that DNA Pol III detects

Answer 14

Primer

Question 15

Direction of exonuclease activity

Answer 15

3’-5’

Question 16

Seals nicks in Okazaki fragments by catalyzing phospholipid ter linkages

Answer 16

DNA ligase

Question 17

Highly repetitive TG-repeats at the ends of linear chromosomes

Answer 17

Telomeres

Question 18

Number of times a human cell can divide

Answer 18

Hayflick Limit

Question 19

Jumping Genes

Answer 19

Transposons