Basic Transcriptional Control Mechanisms Flashcards

0
Q

Proteins or structural motifs that may be produced on one chromosome but act on another

A

Trans-acting molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

DNA sequences which influence gene expression on the same chromosome

A

Cis-acting elements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Genes involved in a linear array regulated by a single promoter

A

Operon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Smallest unit of genetic expression

A

Cistron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Conditions for lacI to be repressed in E. coli

A

High glucose, low lactose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Protein synthesized by lacZ

A

Beta galactosidase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Protein synthesized by lacY

A

Lactose permease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Protein synthesized by lacA

A

Thiogalactoside transacetylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Binds to Lac repressor and prevents RNA Pol from recognizing Lac operator

A

Allolactose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Causes attachment of RNA polymerase to promoter region to allow synthesis of beta galactosidase, lactose permease, and thiogalactoside transacetyase

A

CAP-cAMP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/F: the histidine operon synthesizes the histidine attenuator only when histidine is already present

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pathway preferred for bacteriophage lambda under favorable growth conditions

A

Lytic growth pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

T/F: eukaryotic gene expression is polycistronic.

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Molecule responsible for splicing exons together

A

Spliceosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Region of DNA that includes signals for transcription initiation, elongation, and termination

A

Transcription Unit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

DNA region where RNA Pol binds and initiates transcription

A

Promoter Region; pribnow in prokaryotes, hogness-goldberg in eukaryotes

16
Q

Two eukaryotic promoters

A

TATA, DPE (downstream promoter element)

17
Q

Promoter which tells you how frequent synthesis should occur

A

CAAT box

18
Q

Increases rate of transcription when bound to transcription factors; function in a location-independent fashion

A

Enhancer protein

19
Q

Recognizable domains in transcription factors

A

DNA-binding domain, activation domain

20
Q

Motifs in DNA-binding domain

A

Zinc fingers, leucine zipper, helix-turn-helix

21
Q

Transcription factor which binds to Hogness-Goldberg box

A

TFIID

22
Q

Counterpart of TFIIF in prokaryotes

A

Sigma growth factor

23
Q

Transcription factor that functions as bank lock in ‘multiple locks, multiple keys’ model

A

Core promoter