Basic Transcriptional Control Mechanisms

Question 0

Proteins or structural motifs that may be produced on one chromosome but act on another

Answer 0

Trans-acting molecules

Question 1

DNA sequences which influence gene expression on the same chromosome

Answer 1

Cis-acting elements

Question 2

Genes involved in a linear array regulated by a single promoter

Answer 2

Operon

Question 3

Smallest unit of genetic expression

Answer 3

Cistron

Question 4

Conditions for lacI to be repressed in E. coli

Answer 4

High glucose, low lactose

Question 5

Protein synthesized by lacZ

Answer 5

Beta galactosidase

Question 6

Protein synthesized by lacY

Answer 6

Lactose permease

Question 7

Protein synthesized by lacA

Answer 7

Thiogalactoside transacetylase

Question 8

Binds to Lac repressor and prevents RNA Pol from recognizing Lac operator

Answer 8

Allolactose

Question 9

Causes attachment of RNA polymerase to promoter region to allow synthesis of beta galactosidase, lactose permease, and thiogalactoside transacetyase

Answer 9

CAP-cAMP

Question 10

T/F: the histidine operon synthesizes the histidine attenuator only when histidine is already present

Answer 10

TRUE

Question 11

Pathway preferred for bacteriophage lambda under favorable growth conditions

Answer 11

Lytic growth pathway

Question 12

T/F: eukaryotic gene expression is polycistronic.

Answer 12

FALSE

Question 13

Molecule responsible for splicing exons together

Answer 13

Spliceosomes

Question 14

Region of DNA that includes signals for transcription initiation, elongation, and termination

Answer 14

Transcription Unit

Question 15

DNA region where RNA Pol binds and initiates transcription

Answer 15

Promoter Region; pribnow in prokaryotes, hogness-goldberg in eukaryotes

Question 16

Two eukaryotic promoters

Answer 16

TATA, DPE (downstream promoter element)

Question 17

Promoter which tells you how frequent synthesis should occur

Answer 17

CAAT box

Question 18

Increases rate of transcription when bound to transcription factors; function in a location-independent fashion

Answer 18

Enhancer protein

Question 19

Recognizable domains in transcription factors

Answer 19

DNA-binding domain, activation domain

Question 20

Motifs in DNA-binding domain

Answer 20

Zinc fingers, leucine zipper, helix-turn-helix

Question 21

Transcription factor which binds to Hogness-Goldberg box

Answer 21

TFIID

Question 22

Counterpart of TFIIF in prokaryotes

Answer 22

Sigma growth factor

Question 23

Transcription factor that functions as bank lock in ‘multiple locks, multiple keys’ model

Answer 23

Core promoter