DNA Locus Nomenclature (Exam 1)

Question 1

Name 3 ways that DNA loci are named.

Answer 1

1) Disease or trait association
2) Location & discovery
3) G-banding pattern

Question 2

Disease/trait association nomenclature: Why is the tyrosine hydroxylase gene called TH01?

Answer 2

TH - tyrosine hydroxylase enzyme
01 - located on Intron #1

Question 3

Location/discovery nomenclature: Decode gene D21S11.

Answer 3

D - DNA
21 - Chromosome 21
S - single copy
11 - 11th locus on Chromosome 21

Question 4

G-banding: Decode gene 12p3.

Answer 4

12 - Chromosome 12
p - locus on the p-arm of chromosome
3 - 3rd band counting up from the centromere