DM Pharm Trends/Summary Flashcards
1
Q
High A1C lowering
A
Metformin
SUs/Non SUs
GLP-1 agonists
2
Q
Medium A1C lowering
A
TZD
3
Q
Low A1C lowering
A
DPP-4 Inhib
SGLT-2 Inhib
4
Q
Weight loss
A
GLP-1 agonists
SGLT-2 inhib
Metformin
5
Q
Weight neutral
A
DPP-4 inhib
Metformin
6
Q
Weight gain
A
TZD
SUs
Non-SUs
7
Q
Risk factors for Lactic Acidosis
A
More likely if patient has underlying risk factors
- Decreased kidney function
- Tissue hypoxia (e.g., cardiopulmonary disease)
- Liver disease and excessive alcohol use
8
Q
Sx of lactic acidosis
A
Weakness Myalgia Malaise Heavy Labored breathing abd distress
9
Q
Cause HypO-G
A
SU (esp. Glyburide)
Non-SU
Synthetic Amylin Analog
Afrezza
10
Q
Which drug dec LDL?
A
Biguanide
11
Q
Which drugs decrease TG?
A
Biguanide
TZD
12
Q
Which drugs increase HDL?
A
Biguanide
TZD
13
Q
Hypoglycemia symptoms - symp sx
A
palpitations
tremor
sweating
anxiety
14
Q
Hypoglycemia symptoms - parasymp sx
A
hunger
15
Q
Hypoglycemia symptoms - CNS sx
A
neuroglycopenia
