DLA 4+5+6

Question 1

cytotrophoblast vs syncytiotrophoblast

Answer 1

inner cyto: mitotically active and makes cells

outer syn: secretes HCG (indicate pregnancy)

Question 2

ectopic pregnancy
symptoms?
causes?
treatment?

Answer 2

abnormal site of egg implantation

missed period
abdominal pain
bleeding
positive pregnancy test with lower hcg

due to delay or prevention of transport

treatment:
termination of pregnancy
removal of the fallopian tube

Question 3

changes before labor?

target of CRH?

Answer 3

CRH secretion increases

CRH-BP decreases

CRH targets the fetal zone of the adrenal gland to secrete DHEAS, this increases estrogen and progesterone before birth

Question 4

factors that increase contractility?

Answer 4

increase the number of gap junctions in the myometrium

increase in pg production by placenta

increase in amount of oxytocin receptors in myometrium

increase in uterine excitability for estrogen

Question 5

what initiates labor?

Answer 5

the estrogen to progesterone ratio increases closer to birth

there is a rise in prostaglandins

pg F2 and E2 stimulates contractions and dilation of cervix

Question 6

oxytocin and labor?

Answer 6

increase secretion at labor

stretch of the cervix increases oxytocin

the fetus releases oxytocin, cortisol, and pg’s

increase oxytocin increases the intensity of contraction

Question 7

role of oxytocin at the uterine receptor

Answer 7

oxytocin binds to receptor

increase IP3 and DAG and Ca

contraction of SM

Question 8

pitocin?

Answer 8

synthetic oxytocin used to augment or induce labor

2-4 strong contractions every 10 minutes