Disorders of cranial nerves Flashcards

1
Q

Clinical tests used to assess CN II (think examination) (5)

A
Visual acuity – Snellen test
Visual field test
Pupillary reflex
Fundoscopy
Colour vision test
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2
Q

Clinical test used to assess CN III, IV, VI

A

Eye movements - follow finger as it makes a H shape

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3
Q

What are we looking for when testing CN III, IV, VI (4)

A

Evidence of ptosis
Evidence of anisocoria (unequal pupils)
Pupillary reactions
Diplopia

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4
Q

Clinical tests used to assess CN V (4)

A

Sensation (light and heavy touch) in the ophthalmic, maxillary and mandibular areas
Power of the muscles of mastication (masseter and pterygoids)
Corneal reflex
Jaw jerk reflex

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5
Q

Clinical tests used to assess CN VII (3)

A

Movements of the muscles of facial expression

  • Raise eyebrows/wrinkle forehead
  • Squeeze eyes
  • Smile with teeth
  • Puff cheeks

Corneal reflex

Taste

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6
Q

Clinical tests used to assess CN VIII (5)

A

Hearing tests

  • Whisper test
  • Rinne’s test
  • Weber’s test

Balance

  • Dix-hallpike maoeuvre
  • Untenberger’s test
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7
Q

Clinical tests used to assess CN IX & X (4)

A

Movement of the palate – symmetrical/asymmetrical
Gag reflex
Quality of speech – if poor, indicates weakness at back of palate
Quality of cough

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8
Q

Clinical tests used to assess CN XI (2)

A

Head turning - SCM

Shoulder shrugging - trapezius

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9
Q

Clinical tests used to assess CN XII (2)

A

Appearance of tongue - fasciculations, wasting

Movement and power of tongue

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10
Q

What cranial nerve is the afferent and efferent of the pupillary light reflex

A

Afferent - CN II

Efferent - CN III

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11
Q

What cranial nerve is the afferent and efferent of the corneal reflex

A

Afferent – CN V

Efferent – CN VII

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12
Q

What cranial nerve is the afferent and efferent of the jaw jerk reflex

A

Afferent & efferent - CN V

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13
Q

What cranial nerve is the afferent and efferent of the gag reflex

A

Afferent – IX

Efferent - X

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14
Q

Where is the nuclei of CN III & IV

A

Midbrain

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15
Q

Where is the nuclei of CN V, VI & VII

A

Pons

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16
Q

Where is the nuclei of CN VIII

A

Pontomedullary junction

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17
Q

Where is the nuclei of CN IX, X, XI & XII

A

Medulla

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18
Q

What is the angle called where CN VI & VIII emerge

A

Cerebellopontine angle

19
Q

Pure motor signs sometimes may not actually be a cranial nerve lesion but indicate the pure motor disease:

A

Myasthenia gravis

20
Q

Which of the following is an appropriate method of testing coordination of the lower limb:

A Ask the patient to state if his toe is moved up or down, when his eyes are shut

B Assessing the patient’s ability to sit up from lying

C Assessing the plantar response

D Finger-nose test

E Heel-shin test

A

E

21
Q

A 51 year old man is noted to have a left trigeminal nerve palsy.

Which of the following is the most likely examination finding:

He has absent taste sensation to the anterior two thirds of the left of the tongue

B He has numbness over the left mandible

C He has numbness over the right maxilla

D He has numbness over the right posterior aspect of the scalp

E He is unable to smile with the left side of his mouth

A

B

22
Q

Clinical features of optic neuritis (7)

A
Monocular visual loss
Pain on eye movement (as nerve inflamed)
Peri-orbital pain
Reduced visual acuity/ blurry
Reduced colour vision

Optic disc swollen - papilloedema
Relative afferent pupillary defect

23
Q

General trigger of trigeminal neuralgia (a type of headache)

A

Temperature

24
Q

Clinical features of Bell’s palsy (4)

A

Unilateral facial weakness
Dry eye - due to inadequate blinking
Post-auricular pain
Synkinesis - involuntary muscular movements accompanying voluntary movements, e.g. voluntary smiling may induce an involuntary contraction of the eye muscles

25
Q

Bell’s palsy is thought to be due to what

A

Re-activation of herpes simplex virus

26
Q

Treatment of Bell’s palsy (2)

A

High dose steroids

Eye protection - daytime (glasses, artificial tears); Overnight (ophthalmic lubricant, eyelid taped)

27
Q

In UMN facial paralysis, is the forehead preserved

A

Yes, forehead unaffected unlike LMN facial paralysis

28
Q

Clinical features of vestibular neuronitis (inflamed vestibular branch of CN VIII) (3)

A

Disabling vertigo
Vomiting
Nystagmus

29
Q

Vestibular neuronitis thought to be due to what

A

Preceding viral infection

30
Q

Effect of sympathetic system on pupils

A

Dilates pupils

31
Q

Effect of parasympathetic system on pupils

A

Constricts pupils

32
Q

Palsy of what CN leads to a fixed dilated eye

A

CN III

33
Q

Causes of DILATED pupils (7)

A
Youth 
Dim lighting
Anxiety, excitement
“Mydriatic” eye drops
Amphetamine, cocaine overdose
CN III palsy
Brain death – bilateral dilated
34
Q

Causes of CONSTRICTED pupils (5)

A
Old age
Bright light
“Miotic” eye drops 
Opiate overdose
Horner’s Syndrome – small pupil unilaterally
35
Q

Causes of isolated CN III palsy

  • microvascular causes (2)
  • compressive cause (2)
A

Microvascular causes

  • Diabetes
  • Hypertension

Compressive cause

  • posterior communicating artery aneurysm
  • raised ICP
36
Q

Clinical features of microvascular causes v compressive causes of CN III palsy

A

Microvascular causes – PAINLESS, PUPIL UNAFFECTED, NO HEADACHE

Compressive causes – PAINFUL, PUPIL AFFECTED

37
Q

Common cause of isolated CN IV palsy

A

Diabetes

38
Q

Causes of isolated CN VI palsy (4)

A

Idiopathic
Diabetes
Meningitis
Raised ICP

39
Q

Causes of nystagmus (6)

A
Congenital
Serious visual impairment
Peripheral vestibular problem
Central vestibular problem/ brainstem disease
Cerebellar disease
Toxins – medication
40
Q

What is bulbar palsy (LMN or UMN, affecting what CNs)

A

LMN PROBLEM (bilateral LMN lesions affecting CN IX-XII – e.g. MND (motor neurone disease), polio, tumours, syphilis)

41
Q

What is pseudo bulbar palsy (UMN or LMN)

A

Bilateral UMN lesions - e.g. lesion of internal capsule, MND (motor neurone disease))

42
Q

Clinical features of bulbar palsy (4)

A

Wasted fasiculating tongue
Dysarthria
Dysphonia
Dysphagia

43
Q

Clinical features of pseudobulbar palsy (6)

A
Dysarthria
Dysphonia – loss of speech volume
Dysphagia
Spastic, immobile tongue
Brisk jaw jerk
Brisk gag reflex