Anatomy wk 1 Flashcards
Name the parts of the brainstem
Midbrain
Pons
Medulla
What cranial fossa does the brainstem lie in
Posterior
Which part of the diencephalon is immediately superior to the midbrain
Thalamus
Which 2 embryological vesicles give rise to the brainstem
Midbrain (mesencephalon) and hindbrain (rhombencephalon) vesicles
What part of the ventricular system lies within the brainstem
Cerebral aqueduct - in midbrain
What groove separates the pons from the medulla
Pontomedullary junction
Which 3 cranial nerves emerge from the pontomedullary junction
CN VI, VII, VIII
Which cranial nerve has the longest intracranial course + what other Nerve emerging from pontomedullary junction has a long course
CN IV
CN VI
Consequence of CN VI being damaged
CN VI palsy –> unable to abduct eye –> diplopia
3 surface features of the medulla
Pyramids
Olives
Decussation of the pyramids (Can’t actually see this)
What are the pyramids of the medulla made up of
Descending motor fibres (corticobulbar fibres and corticospinal fibres) collectively forming the pyramidal tracts
What 2 tracts collectively form the pyramidal tract
Corticobulbar and corticospinal
What occurs at the decussation of the pyramids
Motor fibres in CST cross over to contralateral side
What are the olives of the medulla made up of
Inferior olivary nuclei
Function of inferior olivary nuclei
Receives motor input from cerebral cortex and has efferent connections with cerebellum to regulate cerebellar motor learning
Posteriorly on the medulla, there’s an open and closed medulla - which of these is superior
Open medulla
What structure does the open part of the medulla open into
IV ventricle
2 surface features of the pons
CN V
Middle cerebellar peduncle
What kind of fibres is the middle cerebellar peduncle made of
Purely afferent (Sensory) fibres
Inferior cerebellar peduncle connects what with what
Medulla with cerebellum
Middle cerebellar peduncle connects what with what
Pons with cerebellum
Superior cerebellar peduncle connects what with what
Midbrain with cerebellum
Surface features of the midbrain
Cerebral peduncles
Superior and inferior colliculi
What fibres are the cerebral peduncles made of
Sensory + motor, but mostly motor
What do the cerebral peduncles connect
Midbrain with thalamus and thereby the cerebrum
Function of superior colliculi
Involved in visual reflex
Function of inferior colliculi
Involved in auditory reflex
4 components of the diencephalon
Thalamus, hypothalamus, subthalamus and epithalamus (pineal gland)
Diencephalon is immediately superior to what
Midbrain
Name the surface projections on the surface of the hypothalamus
Mamillary bodies
Another name for epithalamus
Pineal gland
Name the thing connecting the 2 cerebellar hemispheres in the midline
Vermis
Name the 3 lobes of each cerebellar hemisphere
Anterior lobe
Posterior lobe
Flocculondular lobe
Name the extra lobe like structure of each cerebellar hemisphere inferiorly
Cerebellar tonsil
Name the space anterior to the cerebellum and posterior to brainstem
IV ventricle
Cerebellum sits above what foramen
Foramen magnum
What components of the cerebellum sit above the foramen magnum
Cerebellar tonsils
Clinical significance of cerebellar tonsils
When intracranial pressure suddenly drops, the cerebellar tonsils can herniate down through foramen magnum, compressing lower brainstem and the first part of spinal cord = CEREBELLAR CONING
Posterior inferior cerebellar artery occlusion causes what syndrome
Lateral medullary syndrome
What fissure separates the 2 cerebral hemispheres
Median longitudinal fissure
What fold of dura lies in the median longitudinal fissure
Falx cerebri
What massive white matter tract structure connects the 2 cerebral hemispheres
Corpus callosum
Function of corpus callosum + what fibres it carries
Made up of commissural fibres that allow communication between the right and left side
The cerebral hemispheres sit on which 2 cranial fossae + what sits on the remaining cranial fossa
Anterior and middle
Cerebellum sit on the posterior cranial fossa
What fold of dura mater do the cerebral hemispheres sit above in the posterior cranial fossa
Tentorium cerebelli
Name the fissure that divides the frontal and parietal lobe superiorly and the temporal lobe inferiorly
Lateral fissure
Name the sulcus that divides the frontal and parietal lobe (primary motor cortex from primary somatosensory cortex)
Central sulcus
Name the sulcus on the MEDIAL surface of the cerebral hemispheres that divides the parietal and occipital lobe
Parieto-occipital sulcus
Name the sulcus on the MEDIAL surface of the cerebral hemisphere that extends anteriorly from the parieto-occipital sulcus to the occipital pole posteriorly
Calcarine sulcus
Name the 3 poles of the cerebral hemispheres
Frontal pole
Temporal pole
Occipital pole
Which lobe contains the primary motor cortex
Frontal
Which lobe contains the primary visual cortex
Occipital
Which lobe contains the primary somatosensory cortex
Parietal
Which lobe contains the primary auditory cortex
Temporal
What parts of the vertebrae are removed in a laminectomy
Lamina + spinous process
What muscle overlies the lamina of the vertebrae
Erector spinae
What 4 ligaments might be encountered in a laminectomy
Ligamentum flavum
Interspinous
Supraspinous
Posterior longitudinal
Function of ligaments flavum
Connects laminae of adjacent vertebrae
Broad pale yellow fibrous tissue appearance
Function of interspinous ligament
Connect adjoining spinous processes and extend from the root to apex of spinous processes
Function of supraspinous ligament
Connects the tips of spinous processes from C7 onwards
Function of posterior longitudinal ligament
Connects the posterior surface of vertebral bodies and IV discs; mainly connected to IV discs, less so bodies
What level does spinal cord end in adult
L1-L2
What level does spinal cord end in newborn
L3
What level does the dura mater end
S2
What level does the arachnoid mater end
S2
What happens to the Pia mater inferior to the spinal cord
Extends as the filum terminale
What occupies space between conus medullaris and the termination of the dura and arachnoid mater
Cauda equina (nerve roots of L2- Cc1)
Clinical significance of the caudal equina
Where to do lumbar puncture
What vertebral level would you do lumbar puncture
Between L3 and L4
How many pairs of spinal nerves + describe how many of each
31 pairs - 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccygeal
Lower motor neurone lesion is in where
In spinal nerves that have left the spinal cord (i.e. spinal nerve roots)
LMNs in the ventral horn of spinal cord
Upper motor neuron lesion is in where
CNS - brain and spinal cord
Is damage to the caudal equina an UMN or LMN lesion
LMN
Name the arteries entering the cranial cavity to supply the brain
Right and left vertebral arteries
What happens to the vertebral arteries after entering the foramen magnum
They fuse once they’ve entered the cranial cavity to form basilar artery
Basilar artery terminates as what 2 arteries
Right and left posterior cerebral arteries
Name the small branch that comes off the vertebral arteries before they fuse
Posterior inferior cerebellar arteries
Name the 3 main branches of the basilar artery from posterior to anterior before terminating as the posterior cerebral arteries
Anterior inferior cerebellar a
Labyrinthine a
Superior cerebellar a
What does the posterior communicating artery join
The posterior cerebral a to the middle cerebral/ICA (as MCA is branch of ICA)
What does the anterior communicating artery join
The 2 anterior cerebral arteries
How many posterior and anterior communicating arteries are there
2 posterior
1 anterior
What cerebral arteries are branches of the ICA
Middle and anterior cerebral
Name the arteries forming the circle of willis (4 are paired) that supply the brain
- L+ R INTERNAL CAROTID ARTERY
- L+ R ANTERIOR CEREBRAL ARTERY
- ANTERIOR COMMUNICATING ARTERY
- L+ R POSTERIOR CEREBRAL ARTERY
- L + R POSTERIOR COMMUNICATING ARTERY
Protective function of circle of willis
If one of the arteries that make up the circle of Willis occluded, ischaemia can be prevented because the other arteries would compensate for it by preserving cerebral perfusion through COLLATERAL CIRCULATION
Which arteries do the left and right vertebral arteries arise from
Left and right subclavian
What level range do the left and right ICAs arise
C3 - C5
Which part of brainstem is basilar artery related to
Lies on pons
What fissure does the ACA lie in
What sulcus does the MCA lie in
What fissure does the PCA lie in
Median longitudinal fissure
Lateral sulcus
Transverse/horizontal fissure (between cerebellum and occipital lobe)
Which cerebral artery supplies the: Primary motor cortex Primary somatosensory cortex Primary visual cortex Primary auditory cortex Olfactory area
MCA ACA & MCA PCA MCA MCA?
What parts of brain does the vertebra-basilar system supply
Brainstem
Cerebellum
Occipital lobes
Which arteries runs superior to superior cerebellar arteries
PCAs
Which cranial nerve emerges just above superior cerebellar artery
CN III
Aneurysm of PCA often results in palsy of what closely anatomically related nerve
CN III
Features of CN III palsy
SR, IR, MR, IO wouldn’t function normally
LR and SO can still abduct and depress so eye is typically in down and lateral position
What 3 things help to control blood flow to brain
Carotid sinus
Carotid body
Sympathetic motor nerves
What is the carotid sinus anatomically + function + what nerves are sensory to it
Dilatation on the terminal part of the CCA/proximal part of ICA
Is a pressure receptor which monitors blood flow to brain
Glossopharyngeal and vagus
What is the carotid body anatomically + function + what nerves are sensory to it
Area on the posterior wall of the terminal part of CCA
Contains chemoreceptors which are sensitive to low oxygen (hypoxia), if hypoxia detected then heart rate, respectively rate and blood pressure stimulated to increase
Glossopharyngeal
How are sympathetic motor nerves involved with the ICA
Sympathetic motor nerves from the superior cervical ganglion form a plexus around the ICA and enters the skull with the ICA through the carotid canal
Venous drainage of the brain
By a series of smaller veins which drain into dural venous sinuses
Dural venous sinuses are located between what 2 layers
Cranial dura and the periosteum (inner surface of skull)
Name a cerebral vein belonging to the deep group of cerebral veins that can be seen on specimen
Great cerebral vein
What major vein do dural venous sinuses drain into and through which foramen of the skull does this vein exit
IJV
Jugular
Name the veins that connect the intracranial venous sinuses with extra cranial veins (3) + clinical significance of these
Superior ophthalmic vein
Emissary veins
Inferior petrosal sinuses
Potential routes of infection carried in the blood towards the brain
Superior ophthalmic vein drains into what
Cavernous sinus
What are emissary veins + clinical significance of these
Small veins that connect the dural venous sinuses with the dipole of the skull which contains blood sinuses (in the bone marrow of the dipole) that are continuous with veins in the superficial fascia of the outer part of skull and scalp
Spread infection into brain
What sinus connects the 2 inferior petrosal sinuses
Basilar sinus
Name some dural venous sinuses (8)
Superior saggital Inferior saggital Transverse Sigmoid Cavernous Straight Superior petrosal Inferior petrosal
What bony part of the skull does the confluence of sinuses occur
Internal occipital protuberance
Location of cavernous sinus
On either side of the sella turcica
What vein drains into cavernous sinus
Superior ophthalmic
What neurovascular structures run in the cavernous sinus (6)
ICA
CN III, IV, VI, V1, V2
What structures in skull base is cavernous venous sinus closely related to (3)
Pituitary gland
Sphenoid air sinus
CN II
Serious disease associated with cavernous sinus + describe it
Cavernous sinus thrombosis
Sphenoid air sinus can spread infection into the cavernous venous sinus if a fistula forms between them
Clinical features of cavernous sinus thrombosis
Bulging eyes
Loss of vision (due to impaired venous drainage from orbit + eye –> retinal congestion –> papilloedema or retinal haemorrhages)
Arterial supply to spinal cord
Anterior spinal artery to anterior spinal cord
Posterior spinal artery to posterior spinal cord
Branches of which arteries fuse to form the anterior spinal a
Vertebral a
Posterior spinal a is branch of
Vertebral OR PICA - variable in people
What venous plexus lies in the epidural space + what 2 veins join the plexus
Internal vertebral (epidural) venous plexus Anterior and posterior spinal veins
The internal vertebral venous plexus passes superiorly within the vertebral canal through the …. to communicate with dural sinuses and veins within the skull
Foramen magnum
The internal vertebral venous plexus also communicates with what other plexus on the external surface of the vertebrae
External vertebral venous plexus
3 layers of meninges
Dura mater
Arachnoid mater
Pia mater
What circulates in the subarachnoid space
CSF
What fold of dura is in the midline + what does it separate
Falx cerebri
The 2 hemispheres
What bony structures does the falx cerebri attach anteriorly and posteriorly to
Anterior - crista galli
Posterior - internal occipital protuberance
Name the 4 folds of dura in the brain
Falx cerebri
Tentorium cerebelli
Falx cerebelli
Diaphragma sellae
What dural sinus runs in the upper border of the falx cerebri
Superior saggital
What dural sinus runs in the lower border of the falx cerebri
Inferior saggiata
What structures lie on either side of the tentorium cerebelli
Occipital lobes and cerebellum
What bony points does the anterior edge of the tentorium cerebelli attach to
Clinoid processes of sphenoid bone
What dural venous sinus runs along the attachment of the falx cerebri to the tentorium cerebelli
Straight sinus
What dural fold separates the two cerebellar hemispheres
Falx cerebelli
What dural fold surrounds the pituitary stalk
Diaphragm sellae
Arterial supply of dura mater (3) + name a clinically significant artery that is branch of the maxillary artery that supplies the dura
Branches of ICA, ECA and vertebral a
Middle meningeal
What is the middle meningeal artery a branch of
Maxillary artery which is a branch of ECA
Formane that middle mengineal artery traverses
Foramen spinosum
What are ventricles in the brain
CSF filled cavities
What are ventricles of the brain embryologically derived from
Lumen of neural tube
Name the ventricles + what connects the ventricles to each other
Lateral (2)
3rd
4th
Lateral connected to 3rd by inter ventricular foramen (foramen of munro)
3rd connected to 4th by cerebral aqueduct (of sylvius)
What part of the brain do these parts of the lateral ventricles lie in:
- anterior horn
- body
- inferior horn
- posterior horn
Anterior horn - frontal lobe
Body - under corpus callosum
Inferior - temporal lobe
Posterior - occipital lobe
What part of the brain is the 3rd ventricle in
In the diencephalon, between R + L thalamus
What part of the brain is the cerebral aqueduct in
Midbrain
Where is the 4th ventricle
Posterior to pons + medulla but anterior to cerebellum
What specialised structures in the ventricles produce CSF
Choroid plexus
How does CSF pass into subarachnoid space from 4th ventricle (hint: 2 foramina)
Passes through small holes called the the foramen of Magendie (more medial) and the foramen of Luschka (more lateral) in the roof of the 4th ventricle into the subarachnoid space
How is CSF resorbed once in the subarachnoid space
Via arachnoid villi which protrude into the walls of the superior saggital sinus usually
If CSF circulation restricted –> increase in ICP; in infants congenital defects in circulation of CSF can occur leading to enlargement of the head because ventricles dilated –> degeneration of surrounding brain tissue; what is this called
Hydrocephalus
What surgical procedure can be carried out for hydrocephalus + why
Shunt to redirect fluid out of cerebral circulation into deep venous system
What dural fold separates the occipital lobes from the cerebellum
Tentorium cerebelli
What does cingulate gyrus separate
Separates the frontal and parietal lobes from the cingulate gyrus on the medial surface of the hemisphere