diseases Flashcards
silicosis
silica from sand rock or glass. sandblasters at risk. rock quarry disease
asbestosis
asbestos leads to mesothelioma. malignant tumor
siderosis
iron dust
byssinosis
cotton dust. Brown lung
anthracosis
black lung disease from coal miners. Caplan syndrome= anthracosis +RA
histomycosis/histoplasmosis
endemic fungus around Mississippi or Ohio vallets. Ohio valley fever aka miss. valley fever
coccidiomycosis
endemic fungus in deserts of Southwest. aka San Joaguin valley fever. Valley fever in other states
blastomycosis
endemic fungus on Eastern seaboard. florida to nova scotia
asthma
sputum analysis yeilds Curschmann’s spirals or chrcot leyden crystals
Cystic fibrosis
affects chloride channels. Sweat test. mother notices 1st tastes salt. salty baby syndrome. affects GI and respiratory mucus linings and exocrine secretions. susceptible to pseudomonas aeruginosa. lung transplant required
hemosiderosis
iron in lungs due to bleeding
pulmonary fibrosis
honeycomb lung
tuberculosis
caseous necrosis in lung. gohn complex/lesion. granulomas. epitheloid histiocytes. If spread to spine Potts disease. if vertebra collapses from TB gibbus deformity. Giant epithelial cells
wegener’s granulomatosis
vasculitis of lung and kidney
emphysema
alpha 1 antitrypsin deficiency
azotemia
decreased tubular excretion of nitrogen (increased nitrogen in blood)
hydronephrosis
most commonly caused by prostate problems or ureter stones
kidney stones
nephrolithiasis. most common stone calcium oxalates. kidney stone pain pattern= starts in back and radiates to flanks. once stone in ureters, pain localize in groin
nephritis syndrome
RBCs and small amounts of protein in the urine Eg acute glomerulonephritis (strep pyogenase)
nephrotic syndrome
pre-ecclampsia= HEP, hypertension, edema, proteinurea (massive). ecclampsia=HEP+convulsions +coma =potentially fatal
polycystic kidney
moth eaten appearance
shock
acute tubular necrosis
Wilms
nephroblastoma. mixed tumor of kidney in children (malignant)
Addison’s
decreased cortisol. hypoadrenia. low BP. hyperpigmentation d/t excess ACTH >^MSH. fatiuge
conn’s
excess aldosterone (zona glomerulosa). hypertension. water retention
Cushing’s
excess cortisol (Zona fasciculata). Hyperadrenia. Moon face, buffalo hump, purple straie, central obesity
Goiter
Hyperplasia of thyroid cells due to lack of iodine
Graves disease
hyperthyroidism, causes exophthalmoses (bulging eyes), heat intolerance, weight loss, rapid HR, hair loss. T3&T4 from follicular cells. calcitonin from parafollicular cells
hashimotos
autoimmune cause of hypothyroidism
Myxedema
hypothyroidism. cretinism in the child. cold intolerance, weight gain, slower HR, loss of lateral 1/3 of eyebrows, slow mental faculties (eg memory, common sense) mental retardation