DIS - Retinal Detachment - Week 8 Flashcards
Define retinal detachment, including the layers affected.
Separation/cleavage between the photoreceptors and the RPE
What does retinal detachment result in the opening of? what accummulates?
Results in the reopening of the subretinal space and accumulation of fluid in this space
What happens to the subretinal space during embryonic development?
It closes as optic vesicle invaginates to form the optic cup
Is retinal detachment sight threatening? Is it considered an ocular emergency?
Yes
List the two forms of retinal detachment.
Rhegmatogenous RD
Non-rhegmatogenous RD
Define rhegmatogenous retinal detachment. What is it held open by? What does it facilitate the spread of and where?
Results from a retinal tear/hole
Break is held open by traction
Facilitates the spread of fluid from the liquefied vitreous to the subretinal space
Where are breaks more likely with rhegmatogenous retinal detachment?
More likely within a zone of degeneration
What forms around the hole/tear in rhegmatogenous retinal detachment? What happens to this and due to what(2)?
Localised detachment (cuff)
-usually spreads towards the macula, usually by subretinal fluid
What is meant by secondary non-rhegmatogenous retinal detachment? What can it be caused by?
Retina is pulled from the RPE in the absence of a tear
-caused by major internal disturbance (trauma)
What is meant by tractional non-rhegmatogenous retinal detachment? List three causes.
Shrinkage of fibrovascular vitroretinal membrane
-diabetes, CRVO, BRVO
What is meant by exudative non-rhegmatogenous retinal detachment? What does it occur subsequent to and what is the pathogenesis?
Subsequent to a damaged RPE which permits leakage from the choroid into the subretinal space
List 5 possible causes of exudative non-rhegmatogenous retinal detachment.
AMD
CSR
Choroidal tumour
Intraocular inflammation
Toxaemia of pregnancy
What happens to the incidence of retinal detachment with age? Which age has the highest incidence?
Increases with age, most in mid-50s
Is retinal detachment more common in males, females, or equal?
More in males
Compare the incidence of retinal detachment among caucasians vs asians.
Caucasians»_space; asians
Which age group does trauma related rhegmatogenous retinal detachment tend to occur?
<50
Is there a genetic component to rhegmatogenous retinal detachment?
Yes, 2.6x greater risk if relative diagnosed
List four genetic conditions associated with rhegmatogenous retinal detachment.
Syndromic myopia
Wagner syndrome
Stickler syndrome
Erosive retinopathy
Does myopia increase or decrease the risk of retinal detachment?
Increase
Does cataract surgery increase or decrease the risk of retinal detachment? Explain.
Increases linearly over time due to vitreous structure collapse
-decreased support
Is a retinal hole considered safe once it has pigmented?
Yes
List three abnormal vitreous adhesions that are risk factors for retinal detachment.
Meridional folds
Enclosed oral bays
Granular tissue
Describe how posterior vitreous detachment is a risk factor for retinal detachment, noting which type it can cause (5).
The collapsing vitreous exerts mechanical pull on the retina, causing traction, resulting in haemorrhage or tears -> rhegmatogenous retinal detachment
Summarise the risk factors for retinal detachment (4).
Fellow eye has RD
Positive family ocular history
High myopia
Past cataract surgery