Digestive Flashcards
What medication can increase the risk of developing peptic ulcer disease?
NSAIDS
What is often a cause of dumping syndrome?
Gastric bypass surgery
What enzyme is usually elevated in patients who have PUD?
Pepsin
What are three common causes of Colitis?
Infection
Ischemia
Radiation exposure
What is developmental lactase deficiency?
What is congenital lactase deficiency?
Absence of the lactase enzyme from an autosomal recessive inheritance
What is secondary lactase deficiency?
Loss of lactase resulting from infection, inflammation, or injury to the intestinal mucosa
What are diverticula?
Abnormal out-pouches of wall of the large intestine
What can cause reduced blood flow and can result in death in people with inguinal hernias?
Incarceration
What defect seen in ulcerative colitis typically leads to increased presence of pathogenic antigens in the lumen?
Epithelial barrier and tight junction defects
True or False
Signs and symptoms of ulcerative colitis are bloody diarrhea, mucus discharge, and rectal tenesmus
True
What is characterized as an auto-immune disease causing intestinal inflammation and damage from gluten?
Celiac disease
What layers of the intestine are generally affected by Celiac disease?
Mucosa
What do we define as the relationship and two-way signaling between the CNS and the GI track
Brain-gut interaction
What are the patchy-appearing inflamed wounds, seen with Crohn disease that are interspersed with healthy, normal areas of tissue called?
Skip lesions
What is the peptide that is derived from gluten and often cause damage to the small intestine in individuals with Celiac disease?
Gliadin
True or False
Early detection is crucial of colon cancer because the development takes 10-15 years
True
What are classified as gland-like growths that develop on the intestinal lining?
Polyps
What is the term used for the system that DNA uses to recognize errors and repair those errors by deleting them?
DNA mismatch repair
Increasing prevalence in younger populations (younger than 50) is true for?
Colon cancer
What is one process that can after the normal expression of genes by expressing an incorrect gene or stopping the expression of a correct gene?
Hypermethylation
In relation to incontinence, what occurs when the pudendal nerve is damaged?
If the internal anal sphincter opens, there is no control of the external anal sphincter and defecation occurs
What is the involuntary release of fecal matter or inability to control defecation?
Incontinence
True or False
Anorectal abscesses form as anal glands become obstructed due to infection
True