Digestion II Study Guide Flashcards
term for a bolus of food after it is undergoing digestion in the stomach
chyme
how tunics are modified in stomach
- Muscularis - added internal, oblique layer to allow increased mixing and churning – more intense mechanical breakdown
- Mucosa - contains simple columnar epithelium made entirely of mucous cells – produces a cloudy, protective double layer of alkaline mucus
- Dotted with millions of deep gastric pits
- Gastric pits lead into the gastric glands responsible for producing gastric juice
secretory cells in gastric glands
Mucus neck cells, parietal cells, chief cells, Eneteroendocrine cells
mucus neck cells
produce thin, soluble mucus
Parietal cells
produce HCL (pH 1.5-3.5, required to activate pepsin (breakdown proteins in stomach?)) and secrete intrinsic factor (required to absorb B12)
Chief cells
secrete pepsinogen (inactive pepsin) and lipases
Eneteroendocrine cells
secrete chemical messengers into lamina propria as well as gastrin
Mucosal barrier
produced to protect the stomach
- A thick coating of bicarbonate-rich mucus
- Tight junctions between epithelial cells
- Quick replacement of damaged mucosal cells by stem cells
Gastritis
Inflammation of the stomach in response to breaches of the mucosal barrier
peptic/gastric ulcers
- Erosions of the stomach-wall – cause gnawing, epigastric pain
- Pain typically appears 1-3 hours after eating and resolves with eating again, ulcers are linked to peritonitis and h. Pylori; a type of acid resistant bacteria
different functions completed in the stomach
Propulsion
Mechanical breakdown
Digestion
Absorption
Secretion of intrinsic factor
propulsion
peristalsis
Mechanical breakdown
churning
Absorption
only lipid soluble substances – alcohol and aspirin
Digestion
breakdown of proteins by HCl and pepsin (rennin in infants)
Secretion of intrinsic factor
essential for B12 absorption and maturation of RBCs
Gastrin
hormonal mechanism of regulation of gastric secretion
- Stimulates secretion of hcl by the stomach
- Stimulates secretion of gastrin antagonists by the SI
branch of the ANS that increases gastric secretions
parasympathetic