Diferensiasi sel Flashcards

1
Q

Stem cell adalah

A

Sel pertumbuhan

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2
Q

Karakteristik stem cell

A

Belum berdiferensiasi
Mampu berdiferensiasi
Multipoten
Pluripoten

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3
Q

Faktor internal diferensiasi sel

A

Genetik dan epigenetik

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4
Q

Faktor eksternal diferensiasi sel

A

Lingkungan sekitar sel

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5
Q

Ciri stem cell embrionik

A

Pada embrio
Pluripoten

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6
Q

Ciri stem cell dewasa

A

Diantara sel yang telah berdiferensiasi
Multipoten
Bentuk :
- hematopoietic
- neural
- kulit
- mesenchymal
- jantung

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7
Q

Pemanfaatan stem cell dalam kehidupan

A

Pengobatan regeneratif

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8
Q

Penuaan sel adalah

A

Penurunan progresif masa hidup san aktivitas sel

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9
Q

Abnormalitas pada penuaan sel yaitu akumulasi mutasi dna terjadi karena

A

Radikal bebas mengganggu stabilitas DNA
Terjadi mutasi DNA di sel
Timbul preoksidasi lipid
Gangguan stabilitas membran

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10
Q

Penurunan replikasi sekunder terjadi karena

A

Aktivitas enzim telomerase berkurang
Telomere memendek
Ujung kromosom tidak terlindungi
Dna dianggap rusak
Siklus berhenti
Penurunan replikasi DNA

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11
Q

Defek homeostatis protein disebabkan karena

A

Penurunan translasi protein

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12
Q

Inflamasi persistent terjadi karena

A

Akumulasi sel rusak
Inflamasi ringan menetap
Penyakit kronis
Mempercepat penuaan pada inflamasi yg menumpuk
Memperberat oroses penuaan

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